Summary of Study ST002685

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002685
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Brown Adipose - Untargeted Lipidomics, Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-02
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265885	90252016907	Control	8 weeks of training or control time	Female
SA265886	90266016907	Control	8 weeks of training or control time	Female
SA265887	90265016907	Control	8 weeks of training or control time	Female
SA265888	90239016907	Control	8 weeks of training or control time	Male
SA265889	90237016907	Control	8 weeks of training or control time	Male
SA265890	90217016907	Control	8 weeks of training or control time	Male
SA265891	90229016907	Control	8 weeks of training or control time	Male
SA265892	90232016907	Control	8 weeks of training or control time	Male
SA265893	IPE_Reference_BAT02	QC-Blank	0 hour	-
SA265894	SampleBlank04	QC-Blank	0 hour	-
SA265895	SampleBlank03	QC-Blank	0 hour	-
SA265896	SampleBlank05	QC-Blank	0 hour	-
SA265897	SampleBlank01	QC-Blank	0 hour	-
SA265898	SampleBlank02	QC-Blank	0 hour	-
SA265899	QC01	QC-Pooled	0 hour	-
SA265900	QC05	QC-Pooled	0 hour	-
SA265901	QC09	QC-Pooled	0 hour	-
SA265902	QC07	QC-Pooled	0 hour	-
SA265903	QC06	QC-Pooled	0 hour	-
SA265904	SampleBlank06	QC-Pooled	0 hour	-
SA265905	QC04	QC-Pooled	0 hour	-
SA265906	QC03	QC-Pooled	0 hour	-
SA265907	QC02	QC-Pooled	0 hour	-
SA265908	SED_Reference_BAT	QC-Reference	0 hour	-
SA265909	SED_Reference_BAT02	QC-Reference	0 hour	-
SA265910	IPE_Reference_BAT	QC-Reference	0 hour	-
SA265911	90567016907	Training	1 week of training or control time	Female
SA265912	90571016907	Training	1 week of training or control time	Female
SA265913	90560016907	Training	1 week of training or control time	Female
SA265914	90559016907	Training	1 week of training or control time	Female
SA265915	90430016907	Training	1 week of training or control time	Male
SA265916	90421016907	Training	1 week of training or control time	Male
SA265917	90422016907	Training	1 week of training or control time	Male
SA265918	90423016907	Training	1 week of training or control time	Male
SA265919	90426016907	Training	1 week of training or control time	Male
SA265920	90576016907	Training	2 weeks of training	Female
SA265921	90585016907	Training	2 weeks of training	Female
SA265922	90581016907	Training	2 weeks of training	Female
SA265923	90578016907	Training	2 weeks of training	Female
SA265924	90587016907	Training	2 weeks of training	Female
SA265925	90444016907	Training	2 weeks of training	Male
SA265926	90450016907	Training	2 weeks of training	Male
SA265927	90449016907	Training	2 weeks of training	Male
SA265928	90439016907	Training	2 weeks of training	Male
SA265929	90441016907	Training	2 weeks of training	Male
SA265930	90416016907	Training	4 weeks of training	Female
SA265931	90406016907	Training	4 weeks of training	Female
SA265932	90410016907	Training	4 weeks of training	Female
SA265933	90420016907	Training	4 weeks of training	Female
SA265934	90412016907	Training	4 weeks of training	Female
SA265935	90283016907	Training	4 weeks of training	Male
SA265936	90281016907	Training	4 weeks of training	Male
SA265937	90289016907	Training	4 weeks of training	Male
SA265938	90280016907	Training	4 weeks of training	Male
SA265939	90251016907	Training	8 weeks of training or control time	Female
SA265940	90254016907	Training	8 weeks of training or control time	Female
SA265941	90225016907	Training	8 weeks of training or control time	Male

Showing results 1 to 57 of 57

Showing results 1 to 57 of 57