Summary of Study ST002686

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002686
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Brown Adipose - Untargeted Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-02
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265942	90266016906	Control	8 weeks of training or control time	Female
SA265943	90248016906	Control	8 weeks of training or control time	Female
SA265944	90252016906	Control	8 weeks of training or control time	Female
SA265945	90265016906	Control	8 weeks of training or control time	Female
SA265946	90217016906	Control	8 weeks of training or control time	Male
SA265947	90229016906	Control	8 weeks of training or control time	Male
SA265948	90237016906	Control	8 weeks of training or control time	Male
SA265949	90232016906	Control	8 weeks of training or control time	Male
SA265950	90239016906	Control	8 weeks of training or control time	Male
SA265951	CS00000SB-03	QC-Blank	0 hour	-
SA265952	CS00000SB-05	QC-Blank	0 hour	-
SA265953	CS00000SB-04	QC-Blank	0 hour	-
SA265954	CS00000SB-02	QC-Blank	0 hour	-
SA265955	CS00000PB-04	QC-Blank	0 hour	-
SA265956	CS00000PB-01	QC-Blank	0 hour	-
SA265957	CS00000PB-02	QC-Blank	0 hour	-
SA265958	CS00000PB-03	QC-Blank	0 hour	-
SA265959	CS00000MP-05	QC-DriftCorrection	0 hour	-
SA265960	CS00000MP-03	QC-DriftCorrection	0 hour	-
SA265961	CS00000MP-06	QC-DriftCorrection	0 hour	-
SA265962	CS00000MP-04	QC-DriftCorrection	0 hour	-
SA265963	CS00000MP-09	QC-DriftCorrection	0 hour	-
SA265964	CS00000MP-02	QC-DriftCorrection	0 hour	-
SA265965	CS00000MP-01	QC-DriftCorrection	0 hour	-
SA265966	CS00000MP-08	QC-DriftCorrection	0 hour	-
SA265967	CS00000MP-07	QC-DriftCorrection	0 hour	-
SA265968	CS0000OP0-03	QC-Pooled	0 hour	-
SA265969	CS0000OP0-05	QC-Pooled	0 hour	-
SA265970	CS0000OP0-04	QC-Pooled	0 hour	-
SA265971	CS0000OP0-02	QC-Pooled	0 hour	-
SA265972	CS0000OP0-01	QC-Pooled	0 hour	-
SA265973	CS0000OP0-06	QC-Pooled	0 hour	-
SA265974	CS0000OP0-07	QC-Pooled	0 hour	-
SA265975	CS000QCMP-03	QC-Pooled	0 hour	-
SA265976	CS000QCMP-02	QC-Pooled	0 hour	-
SA265977	CS000QCMP-01	QC-Pooled	0 hour	-
SA265978	CS000QCMP-04	QC-Pooled	0 hour	-
SA265979	CS0UMRA01-04	QC-ReCAS	0 hour	-
SA265980	CS0UMRA01-01	QC-ReCAS	0 hour	-
SA265981	CS0UMRA01-02	QC-ReCAS	0 hour	-
SA265982	CS0UMRA01-03	QC-ReCAS	0 hour	-
SA265983	CSMR80013-03	QC-Reference	0 hour	-
SA265984	CSMR80013-04	QC-Reference	0 hour	-
SA265985	CSMR80013-02	QC-Reference	0 hour	-
SA265986	CSMR80012-02	QC-Reference	0 hour	-
SA265987	CSMR80012-01	QC-Reference	0 hour	-
SA265988	CSMR80013-01	QC-Reference	0 hour	-
SA265989	CSMR80012-03	QC-Reference	0 hour	-
SA265990	CSMR80012-04	QC-Reference	0 hour	-
SA265991	90567016906	Training	1 week of training or control time	Female
SA265992	90559016906	Training	1 week of training or control time	Female
SA265993	90564016906	Training	1 week of training or control time	Female
SA265994	90560016906	Training	1 week of training or control time	Female
SA265995	90571016906	Training	1 week of training or control time	Female
SA265996	90426016906	Training	1 week of training or control time	Male
SA265997	90423016906	Training	1 week of training or control time	Male
SA265998	90422016906	Training	1 week of training or control time	Male
SA265999	90430016906	Training	1 week of training or control time	Male
SA266000	90421016906	Training	1 week of training or control time	Male
SA266001	90576016906	Training	2 weeks of training	Female
SA266002	90578016906	Training	2 weeks of training	Female
SA266003	90581016906	Training	2 weeks of training	Female
SA266004	90587016906	Training	2 weeks of training	Female
SA266005	90585016906	Training	2 weeks of training	Female
SA266006	90441016906	Training	2 weeks of training	Male
SA266007	90449016906	Training	2 weeks of training	Male
SA266008	90450016906	Training	2 weeks of training	Male
SA266009	90439016906	Training	2 weeks of training	Male
SA266010	90444016906	Training	2 weeks of training	Male
SA266011	90412016906	Training	4 weeks of training	Female
SA266012	90410016906	Training	4 weeks of training	Female
SA266013	90416016906	Training	4 weeks of training	Female
SA266014	90420016906	Training	4 weeks of training	Female
SA266015	90406016906	Training	4 weeks of training	Female
SA266016	90280016906	Training	4 weeks of training	Male
SA266017	90281016906	Training	4 weeks of training	Male
SA266018	90283016906	Training	4 weeks of training	Male
SA266019	90289016906	Training	4 weeks of training	Male
SA266020	90292016906	Training	4 weeks of training	Male
SA266021	90251016906	Training	8 weeks of training or control time	Female
SA266022	90258016906	Training	8 weeks of training or control time	Female
SA266023	90267016906	Training	8 weeks of training or control time	Female
SA266024	90254016906	Training	8 weeks of training or control time	Female
SA266025	90227016906	Training	8 weeks of training or control time	Male
SA266026	90222016906	Training	8 weeks of training or control time	Male
SA266027	90225016906	Training	8 weeks of training or control time	Male

Showing results 1 to 86 of 86

Showing results 1 to 86 of 86