Summary of Study ST002687

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002687
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Brown Adipose - Untargeted Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-02
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA266028	90266016906	Control	8 weeks of training or control time	Female
SA266029	90248016906	Control	8 weeks of training or control time	Female
SA266030	90252016906	Control	8 weeks of training or control time	Female
SA266031	90265016906	Control	8 weeks of training or control time	Female
SA266032	90217016906	Control	8 weeks of training or control time	Male
SA266033	90229016906	Control	8 weeks of training or control time	Male
SA266034	90237016906	Control	8 weeks of training or control time	Male
SA266035	90232016906	Control	8 weeks of training or control time	Male
SA266036	90239016906	Control	8 weeks of training or control time	Male
SA266037	CS00000SB-03	QC-Blank	0 hour	-
SA266038	CS00000SB-05	QC-Blank	0 hour	-
SA266039	CS00000SB-04	QC-Blank	0 hour	-
SA266040	CS00000SB-02	QC-Blank	0 hour	-
SA266041	CS00000PB-04	QC-Blank	0 hour	-
SA266042	CS00000PB-01	QC-Blank	0 hour	-
SA266043	CS00000PB-02	QC-Blank	0 hour	-
SA266044	CS00000PB-03	QC-Blank	0 hour	-
SA266045	CS00000MP-05	QC-DriftCorrection	0 hour	-
SA266046	CS00000MP-03	QC-DriftCorrection	0 hour	-
SA266047	CS00000MP-06	QC-DriftCorrection	0 hour	-
SA266048	CS00000MP-04	QC-DriftCorrection	0 hour	-
SA266049	CS00000MP-09	QC-DriftCorrection	0 hour	-
SA266050	CS00000MP-02	QC-DriftCorrection	0 hour	-
SA266051	CS00000MP-01	QC-DriftCorrection	0 hour	-
SA266052	CS00000MP-08	QC-DriftCorrection	0 hour	-
SA266053	CS00000MP-07	QC-DriftCorrection	0 hour	-
SA266054	CS0000OP0-03	QC-Pooled	0 hour	-
SA266055	CS0000OP0-05	QC-Pooled	0 hour	-
SA266056	CS0000OP0-04	QC-Pooled	0 hour	-
SA266057	CS0000OP0-02	QC-Pooled	0 hour	-
SA266058	CS0000OP0-01	QC-Pooled	0 hour	-
SA266059	CS0000OP0-06	QC-Pooled	0 hour	-
SA266060	CS0000OP0-07	QC-Pooled	0 hour	-
SA266061	CS000QCMP-03	QC-Pooled	0 hour	-
SA266062	CS000QCMP-02	QC-Pooled	0 hour	-
SA266063	CS000QCMP-01	QC-Pooled	0 hour	-
SA266064	CS000QCMP-04	QC-Pooled	0 hour	-
SA266065	CS0UMRA01-04	QC-ReCAS	0 hour	-
SA266066	CS0UMRA01-01	QC-ReCAS	0 hour	-
SA266067	CS0UMRA01-02	QC-ReCAS	0 hour	-
SA266068	CS0UMRA01-03	QC-ReCAS	0 hour	-
SA266069	CSMR80013-03	QC-Reference	0 hour	-
SA266070	CSMR80013-04	QC-Reference	0 hour	-
SA266071	CSMR80013-02	QC-Reference	0 hour	-
SA266072	CSMR80012-02	QC-Reference	0 hour	-
SA266073	CSMR80012-01	QC-Reference	0 hour	-
SA266074	CSMR80013-01	QC-Reference	0 hour	-
SA266075	CSMR80012-03	QC-Reference	0 hour	-
SA266076	CSMR80012-04	QC-Reference	0 hour	-
SA266077	90567016906	Training	1 week of training or control time	Female
SA266078	90559016906	Training	1 week of training or control time	Female
SA266079	90564016906	Training	1 week of training or control time	Female
SA266080	90560016906	Training	1 week of training or control time	Female
SA266081	90571016906	Training	1 week of training or control time	Female
SA266082	90426016906	Training	1 week of training or control time	Male
SA266083	90423016906	Training	1 week of training or control time	Male
SA266084	90422016906	Training	1 week of training or control time	Male
SA266085	90430016906	Training	1 week of training or control time	Male
SA266086	90421016906	Training	1 week of training or control time	Male
SA266087	90576016906	Training	2 weeks of training	Female
SA266088	90578016906	Training	2 weeks of training	Female
SA266089	90581016906	Training	2 weeks of training	Female
SA266090	90587016906	Training	2 weeks of training	Female
SA266091	90585016906	Training	2 weeks of training	Female
SA266092	90441016906	Training	2 weeks of training	Male
SA266093	90449016906	Training	2 weeks of training	Male
SA266094	90450016906	Training	2 weeks of training	Male
SA266095	90439016906	Training	2 weeks of training	Male
SA266096	90444016906	Training	2 weeks of training	Male
SA266097	90412016906	Training	4 weeks of training	Female
SA266098	90410016906	Training	4 weeks of training	Female
SA266099	90416016906	Training	4 weeks of training	Female
SA266100	90420016906	Training	4 weeks of training	Female
SA266101	90406016906	Training	4 weeks of training	Female
SA266102	90280016906	Training	4 weeks of training	Male
SA266103	90281016906	Training	4 weeks of training	Male
SA266104	90283016906	Training	4 weeks of training	Male
SA266105	90289016906	Training	4 weeks of training	Male
SA266106	90292016906	Training	4 weeks of training	Male
SA266107	90251016906	Training	8 weeks of training or control time	Female
SA266108	90258016906	Training	8 weeks of training or control time	Female
SA266109	90267016906	Training	8 weeks of training or control time	Female
SA266110	90254016906	Training	8 weeks of training or control time	Female
SA266111	90227016906	Training	8 weeks of training or control time	Male
SA266112	90222016906	Training	8 weeks of training or control time	Male
SA266113	90225016906	Training	8 weeks of training or control time	Male

Showing results 1 to 86 of 86

Showing results 1 to 86 of 86