Summary of Study ST002690

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002690
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:White Adipose - Untargeted Lipidomics, Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-02
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA266270	90248017009	Control	8 weeks of training or control time	Female
SA266271	90265017009	Control	8 weeks of training or control time	Female
SA266272	90252017009	Control	8 weeks of training or control time	Female
SA266273	90266017009	Control	8 weeks of training or control time	Female
SA266274	90245017009	Control	8 weeks of training or control time	Female
SA266275	90232017009	Control	8 weeks of training or control time	Male
SA266276	90229017009	Control	8 weeks of training or control time	Male
SA266277	90239017009	Control	8 weeks of training or control time	Male
SA266278	90237017009	Control	8 weeks of training or control time	Male
SA266279	90217017009	Control	8 weeks of training or control time	Male
SA266280	SampleBlank06	QC-Blank	0 hour	-
SA266281	SampleBlank02	QC-Blank	0 hour	-
SA266282	SampleBlank04	QC-Blank	0 hour	-
SA266283	SampleBlank05	QC-Blank	0 hour	-
SA266284	SampleBlank01	QC-Blank	0 hour	-
SA266285	SampleBlank03	QC-Blank	0 hour	-
SA266286	QC04	QC-Pooled	0 hour	-
SA266287	QC05	QC-Pooled	0 hour	-
SA266288	QC01	QC-Pooled	0 hour	-
SA266289	QC07	QC-Pooled	0 hour	-
SA266290	QC06	QC-Pooled	0 hour	-
SA266291	QC09	QC-Pooled	0 hour	-
SA266292	QC02	QC-Pooled	0 hour	-
SA266293	QC08	QC-Pooled	0 hour	-
SA266294	QC03	QC-Pooled	0 hour	-
SA266295	IPE_Reference_WAT	QC-Reference	0 hour	-
SA266296	SED_Reference_WAT	QC-Reference	0 hour	-
SA266297	SED_Reference_WAT02	QC-Reference	0 hour	-
SA266298	IPE_Reference_WAT02	QC-Reference	0 hour	-
SA266299	90560017009	Training	1 week of training or control time	Female
SA266300	90564017009	Training	1 week of training or control time	Female
SA266301	90559017009	Training	1 week of training or control time	Female
SA266302	90571017009	Training	1 week of training or control time	Female
SA266303	90567017009	Training	1 week of training or control time	Female
SA266304	90430017009	Training	1 week of training or control time	Male
SA266305	90426017009	Training	1 week of training or control time	Male
SA266306	90421017009	Training	1 week of training or control time	Male
SA266307	90423017009	Training	1 week of training or control time	Male
SA266308	90422017009	Training	1 week of training or control time	Male
SA266309	90578017009	Training	2 weeks of training	Female
SA266310	90581017009	Training	2 weeks of training	Female
SA266311	90585017009	Training	2 weeks of training	Female
SA266312	90587017009	Training	2 weeks of training	Female
SA266313	90576017009	Training	2 weeks of training	Female
SA266314	90439017009	Training	2 weeks of training	Male
SA266315	90441017009	Training	2 weeks of training	Male
SA266316	90450017009	Training	2 weeks of training	Male
SA266317	90444017009	Training	2 weeks of training	Male
SA266318	90449017009	Training	2 weeks of training	Male
SA266319	90412017009	Training	4 weeks of training	Female
SA266320	90406017009	Training	4 weeks of training	Female
SA266321	90410017009	Training	4 weeks of training	Female
SA266322	90416017009	Training	4 weeks of training	Female
SA266323	90420017009	Training	4 weeks of training	Female
SA266324	90283017009	Training	4 weeks of training	Male
SA266325	90289017009	Training	4 weeks of training	Male
SA266326	90281017009	Training	4 weeks of training	Male
SA266327	90280017009	Training	4 weeks of training	Male
SA266328	90292017009	Training	4 weeks of training	Male
SA266329	90254017009	Training	8 weeks of training or control time	Female
SA266330	90258017009	Training	8 weeks of training or control time	Female
SA266331	90267017009	Training	8 weeks of training or control time	Female
SA266332	90251017009	Training	8 weeks of training or control time	Female
SA266333	90259017009	Training	8 weeks of training or control time	Female
SA266334	90225017009	Training	8 weeks of training or control time	Male
SA266335	90223017009	Training	8 weeks of training or control time	Male
SA266336	90218017009	Training	8 weeks of training or control time	Male
SA266337	90222017009	Training	8 weeks of training or control time	Male
SA266338	90227017009	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69