Summary of Study ST002708
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001678. The data can be accessed directly via it's Project DOI: 10.21228/M8T146 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002708 |
| Study Title | Levels of central carbon metabolites in choroid plexus as part of natural diurnal variation |
| Study Summary | This study employs targeted LC-MS analysis of choroid plexus (ChP) tissue to assess relative changes in the levels of intermediates from the central carbon metabolism, with additional attention to mitochondrial energy precursors (ATP/ADP, NAD(P) and NAD(P)H) at two time points in the diurnal cycle. For this purpose, mice were kept in a circadian cabinet housing with 12-hour light cycle (7 a.m. on/ 7 p.m. off) and tissues were collected consistently at an a.m and a p.m time point (9 a.m. and 9 p.m). Two different ChP tissues were collected for analysis (LV - left ventricle and 4V - 4th ventricle). Also two separate extractions were performed: 80% MetOH based ("MetOH" study factor) and FB (MetOH with Na-ascorbate and Na-acetate additives, "FB" study factor). The two extractions are optimal for central carbon metabolites or NAD(P)/H respectively. |
| Institute | Boston Childrens Hospital |
| Department | Pathology |
| Laboratory | Kanarek Lab |
| Last Name | Petrova |
| First Name | Boryana |
| Address | 330 Longwood Av |
| boryana.petrova@childrens.harvard.edu | |
| Phone | 6173557433 |
| Submit Date | 2023-05-15 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-05-28 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Diurnal_Cycle |
|---|---|---|
| SA272290 | RF34 | AM 4V_ChP (FB extraction) |
| SA272291 | RF42 | AM 4V_ChP (FB extraction) |
| SA272292 | RF18 | AM 4V_ChP (FB extraction) |
| SA272293 | RF38 | AM 4V_ChP (FB extraction) |
| SA272294 | RF30 | AM 4V_ChP (FB extraction) |
| SA272295 | RF22 | AM 4V_ChP (FB extraction) |
| SA272296 | RF46 | AM 4V_ChP (FB extraction) |
| SA272297 | RF26 | AM 4V_ChP (FB extraction) |
| SA272298 | RF48 | AM 4V_ChP (MetOH extraction) |
| SA272299 | RF44 | AM 4V_ChP (MetOH extraction) |
| SA272300 | RF40 | AM 4V_ChP (MetOH extraction) |
| SA272301 | RF20 | AM 4V_ChP (MetOH extraction) |
| SA272302 | RF28 | AM 4V_ChP (MetOH extraction) |
| SA272303 | RF24 | AM 4V_ChP (MetOH extraction) |
| SA272304 | RF32 | AM 4V_ChP (MetOH extraction) |
| SA272305 | RF36 | AM 4V_ChP (MetOH extraction) |
| SA272306 | RF25 | AM LV_ChP (FB extraction) |
| SA272307 | RF21 | AM LV_ChP (FB extraction) |
| SA272308 | RF33 | AM LV_ChP (FB extraction) |
| SA272309 | RF37 | AM LV_ChP (FB extraction) |
| SA272310 | RF45 | AM LV_ChP (FB extraction) |
| SA272311 | RF41 | AM LV_ChP (FB extraction) |
| SA272312 | RF29 | AM LV_ChP (FB extraction) |
| SA272313 | RF17 | AM LV_ChP (FB extraction) |
| SA272314 | RF43 | AM LV_ChP (MetOH extraction) |
| SA272315 | RF47 | AM LV_ChP (MetOH extraction) |
| SA272316 | RF35 | AM LV_ChP (MetOH extraction) |
| SA272317 | RF31 | AM LV_ChP (MetOH extraction) |
| SA272318 | RF23 | AM LV_ChP (MetOH extraction) |
| SA272319 | RF27 | AM LV_ChP (MetOH extraction) |
| SA272320 | RF19 | AM LV_ChP (MetOH extraction) |
| SA272321 | RF39 | AM LV_ChP (MetOH extraction) |
| SA272322 | RF58 | PM 4V_ChP (FB extraction) |
| SA272323 | RF66 | PM 4V_ChP (FB extraction) |
| SA272324 | RF54 | PM 4V_ChP (FB extraction) |
| SA272325 | RF70 | PM 4V_ChP (FB extraction) |
| SA272326 | RF50 | PM 4V_ChP (FB extraction) |
| SA272327 | RF78 | PM 4V_ChP (FB extraction) |
| SA272328 | RF74 | PM 4V_ChP (FB extraction) |
| SA272329 | RF62 | PM 4V_ChP (FB extraction) |
| SA272330 | RF52 | PM 4V_ChP (MetOH extraction) |
| SA272331 | RF68 | PM 4V_ChP (MetOH extraction) |
| SA272332 | RF72 | PM 4V_ChP (MetOH extraction) |
| SA272333 | RF76 | PM 4V_ChP (MetOH extraction) |
| SA272334 | RF80 | PM 4V_ChP (MetOH extraction) |
| SA272335 | RF60 | PM 4V_ChP (MetOH extraction) |
| SA272336 | RF56 | PM 4V_ChP (MetOH extraction) |
| SA272337 | RF64 | PM 4V_ChP (MetOH extraction) |
| SA272338 | RF53 | PM LV_ChP (FB extraction) |
| SA272339 | RF77 | PM LV_ChP (FB extraction) |
| SA272340 | RF73 | PM LV_ChP (FB extraction) |
| SA272341 | RF65 | PM LV_ChP (FB extraction) |
| SA272342 | RF61 | PM LV_ChP (FB extraction) |
| SA272343 | RF57 | PM LV_ChP (FB extraction) |
| SA272344 | RF69 | PM LV_ChP (FB extraction) |
| SA272345 | RF49 | PM LV_ChP (FB extraction) |
| SA272346 | RF59 | PM LV_ChP (MetOH extraction) |
| SA272347 | RF63 | PM LV_ChP (MetOH extraction) |
| SA272348 | RF67 | PM LV_ChP (MetOH extraction) |
| SA272349 | RF55 | PM LV_ChP (MetOH extraction) |
| SA272350 | RF71 | PM LV_ChP (MetOH extraction) |
| SA272351 | RF75 | PM LV_ChP (MetOH extraction) |
| SA272352 | RF79 | PM LV_ChP (MetOH extraction) |
| SA272353 | RF51 | PM LV_ChP (MetOH extraction) |
| SA272354 | RF86_A | pool FB 01x_A |
| SA272355 | RF86_B | pool FB 01x_B |
| SA272356 | RF85 | pool FB 03x |
| SA272357 | RF84_C | pool FB 1x |
| SA272358 | RF84_A | pool FB 1x_A |
| SA272359 | RF84_B | pool FB 1x_B |
| SA272360 | RF84_D | pool FB 1x_C |
| SA272361 | RF84 | pool FB 1x_D |
| SA272362 | RF83_A | pool MetOH 01x_A |
| SA272363 | RF83_B | pool MetOH 01x_B |
| SA272364 | RF82 | pool MetOH 03x |
| SA272365 | RF81_A | pool MetOH 1x_A |
| SA272366 | RF81_B | pool MetOH 1x_B |
| SA272367 | RF81_C | pool MetOH 1x_C |
| SA272368 | RF81_D | pool MetOH 1x_D |
| SA272369 | RF81_E | pool MetOH 1x_E |
| Showing results 1 to 80 of 80 |
