Summary of Study ST002761

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001719. The data can be accessed directly via it's Project DOI: 10.21228/M8HF01 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST002761
Study TitleMetabolic responses of normal rat kidneys to a high salt intake (Urine)
Study TypeTime-course metabolomics experiment
Study SummaryIn this study, novel methods were developed which allowed continuous (24/7) measurement of arterial blood pressure and renal blood flow in freely moving rats and the intermittent collection of arterial and renal venous blood to estimate kidney metabolic fluxes of O2 and metabolites. Specifically, the study determined the effects of a high salt (HS; 4.0% NaCl) diet upon whole kidney O2 consumption and arterial and renal venous plasma metabolomic profiles of normal Sprague-Dawley rats. A separate group of rats was studied to determine changes in the cortex and outer medulla tissue metabolomic profiles before and following the switch from a 0.4% to 4.0% NaCl diet.
Institute
Medical College of Wisconsin
DepartmentPhysiology
LaboratoryDr. Allen W. Cowley
Last NameCowley
First NameAllen
Address8701 W. Watertown Plank Rd, Milwaukee, WI 53226
Emailcowley@mcw.edu
Phone4149558277
Submit Date2023-06-26
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2023-07-02
Release Version1
Allen Cowley Allen Cowley
https://dx.doi.org/10.21228/M8HF01
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id local_sample_id Treatment Source CF
SA29096920211015_Cowley3_Urine_14_39-417-HS14-U_C18neg_repHS14 Urine Urine
SA29097020211015_Cowley3_Urine_14_39-417-HS14-U_C18negHS14 Urine Urine
SA29097120211015_Cowley3_Urine_12_51-421-HS14-U_C18negHS14 Urine Urine
SA29097220211015_Cowley3_Urine_15_87-463-HS14-U_C18negHS14 Urine Urine
SA29097320211015_Cowley3_Urine_12_51-421-HS14-U_C18neg_repHS14 Urine Urine
SA29097420211015_Cowley3_Urine_17_75-434-HS14-U_C18negHS14 Urine Urine
SA29097520211101_Cowley3_Urine_20_39-417-HS14-U_HILICnegHS14 Urine Urine
SA29097620211101_Cowley3_Urine_20_39-417-HS14-U_HILICneg_repHS14 Urine Urine
SA29097720211015_Cowley3_Urine_17_75-434-HS14-U_C18neg_repHS14 Urine Urine
SA29097820211015_Cowley3_Urine_5_63-429-HS14-U_C18neg_repHS14 Urine Urine
SA29097920211015_Cowley3_Urine_15_87-463-HS14-U_C18neg_repHS14 Urine Urine
SA29098020211015_Cowley3_Urine_5_63-429-HS14-U_C18negHS14 Urine Urine
SA29098120211025_Cowley3_Urine_19_63-429-HS14-U_HILICpos_repHS14 Urine Urine
SA29098220211025_Cowley3_Urine_19_63-429-HS14-U_HILICposHS14 Urine Urine
SA29098320211025_Cowley3_Urine_16_51-421-HS14-U_HILICpos_repHS14 Urine Urine
SA29098420211025_Cowley3_Urine_16_51-421-HS14-U_HILICposHS14 Urine Urine
SA29098520211025_Cowley3_Urine_6_87-463-HS14-U_HILICposHS14 Urine Urine
SA29098620211025_Cowley3_Urine_2_39-417-HS14-U_HILICpos_repHS14 Urine Urine
SA29098720211025_Cowley3_Urine_1_75-434-HS14-U_HILICposHS14 Urine Urine
SA29098820211025_Cowley3_Urine_1_75-434-HS14-U_HILICpos_repHS14 Urine Urine
SA29098920211025_Cowley3_Urine_2_39-417-HS14-U_HILICposHS14 Urine Urine
SA29099020211025_Cowley3_Urine_6_87-463-HS14-U_HILICpos_repHS14 Urine Urine
SA29099120211101_Cowley3_Urine_14_87-463-HS14-U_HILICneg_repHS14 Urine Urine
SA29099220211017_Cowley3_Urine_7_39-417-HS14-U_C18pos_repHS14 Urine Urine
SA29099320211017_Cowley3_Urine_7_39-417-HS14-U_C18posHS14 Urine Urine
SA29099420211017_Cowley3_Urine_11_87-463-HS14-U_C18posHS14 Urine Urine
SA29099520211017_Cowley3_Urine_11_87-463-HS14-U_C18pos_repHS14 Urine Urine
SA29099620211017_Cowley3_Urine_15_51-421-HS14-U_C18pos_repHS14 Urine Urine
SA29099720211017_Cowley3_Urine_15_51-421-HS14-U_C18posHS14 Urine Urine
SA29099820211017_Cowley3_Urine_1_75-434-HS14-U_C18pos_repHS14 Urine Urine
SA29099920211017_Cowley3_Urine_1_75-434-HS14-U_C18posHS14 Urine Urine
SA29100020211101_Cowley3_Urine_10_75-434-HS14-U_HILICnegHS14 Urine Urine
SA29100120211101_Cowley3_Urine_3_51-421-HS14-U_HILICneg_rep_20211102184214HS14 Urine Urine
SA29100220211101_Cowley3_Urine_10_75-434-HS14-U_HILICneg_repHS14 Urine Urine
SA29100320211101_Cowley3_Urine_12_63-429-HS14-U_HILICnegHS14 Urine Urine
SA29100420211101_Cowley3_Urine_14_87-463-HS14-U_HILICnegHS14 Urine Urine
SA29100520211101_Cowley3_Urine_12_63-429-HS14-U_HILICneg_repHS14 Urine Urine
SA29100620211017_Cowley3_Urine_19_63-429-HS14-U_C18posHS14 Urine Urine
SA29100720211017_Cowley3_Urine_19_63-429-HS14-U_C18pos_repHS14 Urine Urine
SA29100820211101_Cowley3_Urine_3_51-421-HS14-U_HILICneg_20211102181055HS14 Urine Urine
SA29100920211101_Cowley3_Urine_13_78-434-HS21-U_HILICnegHS21 Urine Urine
SA29101020211101_Cowley3_Urine_13_78-434-HS21-U_HILICneg_repHS21 Urine Urine
SA29101120211101_Cowley3_Urine_8_54-421-HS21-U_HILICneg_repHS21 Urine Urine
SA29101220211015_Cowley3_Urine_7_78-434-HS21-U_C18neg_repHS21 Urine Urine
SA29101320211015_Cowley3_Urine_16_66-429-HS21-U_C18negHS21 Urine Urine
SA29101420211015_Cowley3_Urine_18_54-421-HS21-U_C18negHS21 Urine Urine
SA29101520211015_Cowley3_Urine_16_66-429-HS21-U_C18neg_repHS21 Urine Urine
SA29101620211015_Cowley3_Urine_7_78-434-HS21-U_C18negHS21 Urine Urine
SA29101720211101_Cowley3_Urine_6_90-463-HS21-U_HILICneg_repHS21 Urine Urine
SA29101820211015_Cowley3_Urine_4_90-463-HS21-U_C18negHS21 Urine Urine
SA29101920211101_Cowley3_Urine_4_42-417-HS21-U_HILICnegHS21 Urine Urine
SA29102020211101_Cowley3_Urine_4_42-417-HS21-U_HILICneg_repHS21 Urine Urine
SA29102120211015_Cowley3_Urine_4_90-463-HS21-U_C18neg_repHS21 Urine Urine
SA29102220211015_Cowley3_Urine_6_42-417-HS21-U_C18negHS21 Urine Urine
SA29102320211015_Cowley3_Urine_18_54-421-HS21-U_C18neg_repHS21 Urine Urine
SA29102420211101_Cowley3_Urine_8_54-421-HS21-U_HILICnegHS21 Urine Urine
SA29102520211015_Cowley3_Urine_6_42-417-HS21-U_C18neg_repHS21 Urine Urine
SA29102620211025_Cowley3_Urine_11_42-417-HS21-U_HILICpos_repHS21 Urine Urine
SA29102720211017_Cowley3_Urine_2_90-463-HS21-U_C18pos_repHS21 Urine Urine
SA29102820211017_Cowley3_Urine_2_90-463-HS21-U_C18posHS21 Urine Urine
SA29102920211017_Cowley3_Urine_9_42-417-HS21-U_C18pos_repHS21 Urine Urine
SA29103020211017_Cowley3_Urine_17_66-429-HS21-U_C18pos_repHS21 Urine Urine
SA29103120211017_Cowley3_Urine_6_54-421-HS21-U_C18posHS21 Urine Urine
SA29103220211017_Cowley3_Urine_6_54-421-HS21-U_C18pos_repHS21 Urine Urine
SA29103320211101_Cowley3_Urine_5_66-429-HS21-U_HILICneg_rep_20211102204731HS21 Urine Urine
SA29103420211101_Cowley3_Urine_6_90-463-HS21-U_HILICnegHS21 Urine Urine
SA29103520211017_Cowley3_Urine_9_42-417-HS21-U_C18posHS21 Urine Urine
SA29103620211025_Cowley3_Urine_3_66-429-HS21-U_HILICposHS21 Urine Urine
SA29103720211017_Cowley3_Urine_17_66-429-HS21-U_C18posHS21 Urine Urine
SA29103820211017_Cowley3_Urine_10_78-434-HS21-U_C18pos_repHS21 Urine Urine
SA29103920211025_Cowley3_Urine_11_42-417-HS21-U_HILICposHS21 Urine Urine
SA29104020211025_Cowley3_Urine_9_54-421-HS21-U_HILICpos_repHS21 Urine Urine
SA29104120211025_Cowley3_Urine_9_54-421-HS21-U_HILICposHS21 Urine Urine
SA29104220211025_Cowley3_Urine_3_66-429-HS21-U_HILICpos_repHS21 Urine Urine
SA29104320211017_Cowley3_Urine_10_78-434-HS21-U_C18posHS21 Urine Urine
SA29104420211025_Cowley3_Urine_14_90-463-HS21-U_HILICposHS21 Urine Urine
SA29104520211025_Cowley3_Urine_17_78-434-HS21-U_HILICpos_repHS21 Urine Urine
SA29104620211025_Cowley3_Urine_17_78-434-HS21-U_HILICposHS21 Urine Urine
SA29104720211025_Cowley3_Urine_14_90-463-HS21-U_HILICpos_repHS21 Urine Urine
SA29104820211101_Cowley3_Urine_5_66-429-HS21-U_HILICneg_20211102201612HS21 Urine Urine
SA29104920211101_Cowley3_Urine_1_60-426-HS7-U_HILICneg_20211102160537HS7 Urine Urine
SA29105020211101_Cowley3_Urine_9_48-421-HS7-U_HILICnegHS7 Urine Urine
SA29105120211101_Cowley3_Urine_7_84-463-HS7-U_HILICneg_repHS7 Urine Urine
SA29105220211101_Cowley3_Urine_7_84-463-HS7-U_HILICnegHS7 Urine Urine
SA29105320211101_Cowley3_Urine_1_60-426-HS7-U_HILICneg_rep_20211102163657HS7 Urine Urine
SA29105420211025_Cowley3_Urine_20_84-463-HS7-U_HILICposHS7 Urine Urine
SA29105520211025_Cowley3_Urine_7_48-421-HS7-U_HILICposHS7 Urine Urine
SA29105620211025_Cowley3_Urine_5_72-434-HS7-U_HILICpos_repHS7 Urine Urine
SA29105720211025_Cowley3_Urine_5_72-434-HS7-U_HILICposHS7 Urine Urine
SA29105820211101_Cowley3_Urine_9_48-421-HS7-U_HILICneg_repHS7 Urine Urine
SA29105920211025_Cowley3_Urine_7_48-421-HS7-U_HILICpos_repHS7 Urine Urine
SA29106020211025_Cowley3_Urine_10_60-429-HS7-U_HILICposHS7 Urine Urine
SA29106120211025_Cowley3_Urine_3_36-417-HS7-U_HILICpos_repHS7 Urine Urine
SA29106220211025_Cowley3_Urine_3_36-417-HS7-U_HILICposHS7 Urine Urine
SA29106320211025_Cowley3_Urine_10_60-429-HS7-U_HILICpos_repHS7 Urine Urine
SA29106420211025_Cowley3_Urine_20_84-463-HS7-U_HILICpos_repHS7 Urine Urine
SA29106520211015_Cowley3_Urine_9_36-417-HS7-U_C18negHS7 Urine Urine
SA29106620211015_Cowley3_Urine_2_84-463-HS7-U_C18negHS7 Urine Urine
SA29106720211101_Cowley3_Urine_11_36-417-HS7-U_HILICnegHS7 Urine Urine
SA29106820211015_Cowley3_Urine_2_84-463-HS7-U_C18neg_repHS7 Urine Urine
Showing page 1 of 3     Results:    1  2  3  Next     Showing results 1 to 100 of 232
  logo