Summary of Study ST001114

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000745. The data can be accessed directly via it's Project DOI: 10.21228/M8CQ42 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files
Study IDST001114
Study TitleMetabolomics profile of umbilical cord blood is associated with maternal pre-pregnant obesity in a perspective multi-ethnic cohort displaying health disparities
Study SummaryMaternal obesity has become a growing global health concern that impacts fetal health and subsequently predisposes the offspring to medical conditions later in life. However, the molecular link between abnormal fetal metabolomic profiles and maternal obesity has not yet been fully elucidated. In this study, we report new discoveries from the newborn cord blood metabolomes associated with a case-control maternal obesity cohort, collected from multi-ethnic populations in Hawaii, including rarely reported Native Hawaiian and other Pacific Islanders (NHPI). This cohort displays significant maternal obesity disparities by subjects’ residential area average income and health insurance. An elastic net penalized logistic regression model was constructed to associate cord blood metabolomics and demographic/physiological information to maternal obesity, with accuracy as high as 0.947. We identify 29 metabolites as early-life biomarkers manifesting intrauterine effect of maternal obesity.
University of Hawaii
DepartmentEpidemiology, Cancer Center
Last NameGarmire
First NameLana
Address701 Ilalo Street
Submit Date2018-03-08
Num Groups2
Total Subjects57
Raw Data File Type(s)cdf
Analysis Type DetailLC-MS
Release Date2019-01-22
Release Version1
Lana Garmire Lana Garmire application/zip

Select appropriate tab below to view additional metadata details:

Combined analysis:

Analysis ID AN001810
Analysis type MS
Chromatography type Reversed phase
Chromatography system Waters Acquity
Column Waters ACQUITY UPLC BEH C18 (1.7um)
MS instrument type Triple quadrupole
MS instrument name Waters Xevo-TQ-S
Units intensity


MS ID:MS001668
Analysis ID:AN001810
Instrument Name:Waters Xevo-TQ-S
Instrument Type:Triple quadrupole
Capillary Temperature:150 °C
Capillary Voltage:3.9V
Collision Energy:20V
Collision Gas:0.17 mL/Min
Dry Gas Flow:150 L/Hr
Dry Gas Temp:350 °C