Summary of Study ST002702
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001673. The data can be accessed directly via it's Project DOI: 10.21228/M8FQ4P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002702 |
| Study Title | A targeted metabolomics approach for sepsis-induced ARDS and its subphenotypes |
| Study Summary | Acute respiratory distress syndrome (ARDS) is etiologically and clinically a heterogeneous disease. Its diagnostic characteristics and subtype classification, and the application of these features to treatment, have been of considerable interest. Metabolomics is becoming important for identifying ARDS biology and distinguishing its subtypes. This study aimed to identify metabolites that could distinguish sepsis-induced ARDS patients from non-ARDS controls, using a targeted metabolomics approach, and to identify whether sepsis-induced direct and sepsis-induced indirect ARDS are metabolically distinct groups, and if so, confirm their metabolites and associated pathways. |
| Institute | Asan Medical Center |
| Last Name | Yoo |
| First Name | Hyun Ju |
| Address | 88, Olympic-ro 43-gil, Songpa-gu |
| d131108@ulsan.ac.kr | |
| Phone | 0230104029 |
| Submit Date | 2023-05-15 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | OTHER |
| Analysis Type Detail | GC-MS/LC-MS |
| Release Date | 2023-07-06 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN004379 | AN004380 | AN004381 | AN004382 |
|---|---|---|---|---|
| Analysis type | MS | MS | MS | MS |
| Chromatography type | Reversed phase | Reversed phase | Reversed phase | GC |
| Chromatography system | Agilent 1290 | Agilent 1290 | Thermo Dionex Ultimate 3000 | Agilent 7890A |
| Column | Phenomenex Synergi Fusion-RP (100 x 4.6mm,4um) | Agilent ZORBAX Eclipse Plus C18 (50 x 2.1mm,1.8um) | Phenomenex Jupiter C18 (150 x 2mm,5um) | Agilent HP5-MS (30m x 0.25mm, 0.25 um) |
| MS Type | ESI | ESI | ESI | EI |
| MS instrument type | QTRAP | QTRAP | Orbitrap | Single quadrupole |
| MS instrument name | ABI Sciex 5500 QTrap | ABI Sciex 5500 QTrap | Thermo LTQ XL | Agilent 5975C |
| Ion Mode | NEGATIVE | POSITIVE | NEGATIVE | POSITIVE |
| Units | nM | uM | ug/uL | area ratio |
MS:
| MS ID: | MS004128 |
| Analysis ID: | AN004379 |
| Instrument Name: | ABI Sciex 5500 QTrap |
| Instrument Type: | QTRAP |
| MS Type: | ESI |
| MS Comments: | Analyst1.5.2 |
| Ion Mode: | NEGATIVE |
| MS ID: | MS004129 |
| Analysis ID: | AN004380 |
| Instrument Name: | ABI Sciex 5500 QTrap |
| Instrument Type: | QTRAP |
| MS Type: | ESI |
| MS Comments: | Analyst1.5.2 |
| Ion Mode: | POSITIVE |
| MS ID: | MS004130 |
| Analysis ID: | AN004381 |
| Instrument Name: | Thermo LTQ XL |
| Instrument Type: | Orbitrap |
| MS Type: | ESI |
| MS Comments: | Xcalibur, SRM |
| Ion Mode: | NEGATIVE |
| MS ID: | MS004131 |
| Analysis ID: | AN004382 |
| Instrument Name: | Agilent 5975C |
| Instrument Type: | Single quadrupole |
| MS Type: | EI |
| MS Comments: | Chemstatation, SRM |
| Ion Mode: | POSITIVE |
