Summary of Study ST001300
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000881. The data can be accessed directly via it's Project DOI: 10.21228/M8T38D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001300 |
| Study Title | Luminal metabolome profiles ofUC-HMA mice transplanted with a healthy human-derived fecal microbiota (FMT). |
| Study Summary | Luminal (fecal) metabolome of FMT treated UC-HMA mice and FMT untreated UC-HMA mice were compared. |
| Institute | University of Michigan |
| Department | Internal Medicine |
| Last Name | Kamada |
| First Name | Nobuhiko |
| Address | 1150 W Medical center Dr, Ann Arbor, MI 48109, USA |
| nkamada@umich.edu | |
| Phone | +1-734-763-2142 |
| Submit Date | 2019-12-24 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2020-01-08 |
| Release Version | 1 |
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Project:
| Project ID: | PR000881 |
| Project DOI: | doi: 10.21228/M8T38D |
| Project Title: | Luminal metabolome profiles ofUC-HMA mice transplanted with a healthy human-derived fecal microbiota (FMT). |
| Project Summary: | We found that UC-HMA mice, GF mice were colonized with gut microbiota derived from patients with UC, were susceptible to Clostridioides difficile (C. difficile) infection. However, FMT almost completely prevented the growth of C. difficile in the gut of UC-HMA mice. To clear this mechanism, fecal samples were collected from FMT-treated and -untreated UC-HMA mice, and metabolite profiles of them were analyzed. |
| Institute: | University of Michigan |
| Department: | Internal Medicine |
| Last Name: | Kamada |
| First Name: | Nobuhiko |
| Address: | 1150 W Medical center Dr, Ann Arbor, MI 48109, USA |
| Email: | nkamada@umich.edu |
| Phone: | +1-734-763-2142 |
