Summary of Study ST002441

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001572. The data can be accessed directly via it's Project DOI: 10.21228/M8H70Z This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002441
Study TitleImpacts of interactions between environmental chemical exposures and diet on gut microbiota and microbiota-derived metabolites in mothers and children (MARCH Cohort)
Study TypeProspective Cohort Study
Study SummaryMARCH is a prospective population based pregnancy cohort that recruited pregnant participants from 2017-2023 from 11 sites within Michigan. Women over 18 years of age were recruited at first prenatal visit and had 3 data collection points focused around each trimester of pregnancy. Blood, urine, and questionnaire data were collected at each prenatal visit. At birth placenta was collected and after birth, infants were assessed at 3 months, 9 months, and yearly. For more information on MARCH please contact Jean Kerver; kerverje@msu.edu This research was supported by the Environmental influences on Child Health Outcomes (ECHO) OIF program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. MARCH is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375 ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382 North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857 Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; U24 ES026539
Institute
Wayne State University
DepartmentPharmacology
Last NamePetriello
First NameMichael
Address6135 Woodward Ave, Detroit, MI 48202
Emailmichael.petriello@wayne.edu
Phone313-577-1089
Submit Date2023-01-12
Total Subjects65
Study CommentsECHO Project EC0549, HHEAR Project E020-0012
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2024-01-12
Release Version1
Michael Petriello Michael Petriello
https://dx.doi.org/10.21228/M8H70Z
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR001572
Project DOI:doi: 10.21228/M8H70Z
Project Title:Impacts of interactions between environmental chemical exposures and diet on gut microbiota and microbiota-derived metabolites in mothers and children
Project Type:C18 Reversed-Phase Broad Spectrum Metabolomics
Project Summary:This project is funded by the NIH Environmental influences on Child Health Outcomes (ECHO) OIF program, and uses data from two cohorts: MAAP and MARCH. This project will examine associations with PFAS exposures and gut microbiota form and function in mothers and children over time. Untargeted metabolomics will be used as a means to assess changes in microbiota-derived metabolites.
Institute:NC HHEAR Hub
Department:Untargeted Analysis
Laboratory:Sumner Lab
Last Name:Li
First Name:Yuanyuan
Address:Nutrition Research Institute, UNC-CH, 500 Laureate Way, Kannapolis, NC 28081
Email:yuanyli4@unc.edu
Phone:984-377-0693
Funding Source:This research was supported by the Environmental influences on Child Health Outcomes (ECHO) OIF program, Office of The Director, National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. MAAP is an ECHO cohort which is supported by the following ECHO Program Collaborators: ECHO Coordinating Center: Duke Clinical Research Institute, Durham, North Carolina: Smith PB, Newby KL, Benjamin DK; U2C OD023375; ECHO Data Analysis Center: Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland: Jacobson LP; Research Triangle Institute, Durham, North Carolina: Catellier D; U24 OD023382; North Carolina Human Health Exposure Analysis Resource Hub: Research Triangle Institute: Fennell T, University of North Carolina at Chapel Hill: Sumner S, University of North Carolina at Charlotte: Du X; U2C ES030857; Human Health Exposure Analysis Resource Coordinating Center: Westat, Inc., Rockville, Maryland: O’Brien B; (U24 ES026539)
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