Summary of Study ST001232

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000825. The data can be accessed directly via it's Project DOI: 10.21228/M81X1W This work is supported by NIH grant, U2C- DK119886.


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Study IDST001232
Study TitleCombining stage - specificity and metabolomic profiling to advance drug discovery for malaria
Study TypeDrug Exposure
Study SummaryMetabolic examination/confirmation of MoA stage-specificity observed in study
Pennsylvania State University
LaboratoryLlinás Laboratory
Last NameOwen
First NameEdward
Address6014 Goldenrod Court
Submit Date2019-07-09
Analysis Type DetailLC-MS
Release Date2020-03-03
Release Version1
Edward Owen Edward Owen application/zip

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Sample Preparation:

Sampleprep ID:SP001308
Sampleprep Summary:Samples washed in PBS, spun down, aspirated, extracted in 90% methanol with labelled aspartate, then dried, resuspended in water labelled with chlorpropamide
Sampleprep Protocol Filename:Metabolite_Extraction_for_LCMS_2017_Llinas.pdf
Processing Method:Wash, Lysis, Drying, resuspension
Processing Storage Conditions:On ice
Extraction Method:90% Methanol Lysis
Extract Cleanup:Centrifugation, pellet removal
Extract Storage:-80℃
Sample Resuspension:100 uL water with chlorpropamide
Sample Spiking:Labelled Aspartate, Chlorpropamide