Summary of Study ST001354
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000924. The data can be accessed directly via it's Project DOI: 10.21228/M8810Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001354 |
| Study Title | 48 hours post-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Patients |
| Study Type | multiple timepoints; patients with severe sepsis or septic shock treated with varying doses of L-carnitine or a saline placebo |
| Study Summary | phase II study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
| Institute | University of Michigan |
| Department | Clinical Pharmacy |
| Laboratory | Stringer NMR Metabolomics Laboratory |
| Last Name | McHugh |
| First Name | Cora |
| Address | 428 Church St, Ann Arbor, MI, 48103, USA |
| NMRmetabolomics@umich.edu | |
| Phone | 7343530164 |
| Submit Date | 2020-04-09 |
| Num Groups | 4 |
| Total Subjects | 228 |
| Num Males | 128 |
| Num Females | 100 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | fid |
| Analysis Type Detail | NMR |
| Release Date | 2020-07-05 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
| Sampleprep ID: | SP001436 |
| Sampleprep Summary: | Methanol precipitation, ultrafiltration |
| Sampleprep Protocol ID: | Methanol precipitation, Ultrafiltration |
| Sampleprep Protocol Filename: | 235.01-Serum_MeOH_Precip_and_Resuspension.pdf Expt._235.1_Filtration_of_CaPS_RACE_Serums.pdf |
| Processing Method: | Methanol precipitation, dried by lyophilization, ultrafiltered |
| Processing Storage Conditions: | On ice |
| Extraction Method: | Methanol precipitation |
| Extract Enrichment: | Lyophilization |
| Sample Resuspension: | 500 uL 50mM sodium phosphate buffer in Deuterium Oxide (D2O) |
| Sample Spiking: | CaFormate internal standard |
