Summary of Study ST002087

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001326. The data can be accessed directly via it's Project DOI: 10.21228/M89T2Q This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002087
Study TitleProfiling metabolites and lipoproteins in COMETA, an Italian cohort of COVID-19 patients
Study TypeNMR-based metabolomics
Study Summary1H NMR spectra of EDTA-plasma from 246 COVID-19-positive subjects in the acute phase of infection were compared to those of 94 COVID-19-recovered subjects. The two cohorts are largely different (discrimination accuracy > 93%) due to a pool of 16 metabolites and 74 lipoprotein parameters significantly up- or down-regulated in the patients and within the healthy range in the recovered subjects. In 28 post-acute COVID-19-positive patients, the metabolites levels are reverted back to normality whereas the lipoprotein parameters are still altered. Therefore, the metabolite biomarkers might be used as the timeliest sign of the individual response to treatment or spontaneous healing.
Institute
University of Florence
DepartmentDepartment of Chemistry
Laboratorymetabolomics
Last NameGhini
First NameVeronica
Addressvia Luigi Sacconi
Emailghini@cerm.unifi.it
Phone+390554574266
Submit Date2022-02-17
Num Groups3
Total Subjects368
Num Males201
Num Females167
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2022-03-16
Release Version1
Veronica Ghini Veronica Ghini
https://dx.doi.org/10.21228/M89T2Q
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Subject:

Subject ID:SU002171
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Gender:Male and female
Human Inclusion Criteria:hospedalized COVID-19 patients
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