Summary of Study ST002462
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001589. The data can be accessed directly via it's Project DOI: 10.21228/M89H8W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002462 |
| Study Title | Tryptophan metabolites in human sera on a defined diet |
| Study Summary | Trp metabolites circulating in serum could provide insight into homeostatic activity of AHR, and we wished to know if the observations in mice could be replicated in humans. Previous work by our group identified AHR activators in human feces, yet it is not clear if these activators are also present in circulation. To address this question, we quantified Trp metabolites in human serum. To mitigate the variable effect of diet on metabolite profiles, we analyzed sera samples collected from study participants fed a defined diet. As with the previously discussed mouse sera, targeted metabolomics was performed on serum samples using LC-MS. |
| Institute | Pennsylvania State University |
| Last Name | DONG |
| First Name | FANGCONG |
| Address | 309 Life Sciences Building, University Park, PA 16802 |
| fxd93@psu.edu | |
| Phone | 8146990203 |
| Submit Date | 2023-01-27 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-02-06 |
| Release Version | 1 |
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Subject:
| Subject ID: | SU002552 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
