Summary of Study ST001985
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001261. The data can be accessed directly via it's Project DOI: 10.21228/M8QD8K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001985 |
| Study Title | Profiling Plasmodium falciparum parasites and human red blood cells after treatment with MMV693183 |
| Study Summary | Compound MMV693183 was added to either Plasmodium falciparum or uninfected red blood cells. The concentrations used were 240 nM, 24 nM, and 2.4 nM. Untreated parasites and red blood cells were also used as controls. |
| Institute | Pennsylvania State University |
| Last Name | Llinás |
| First Name | Manuel |
| Address | W126 Millennium Science Complex, University Park, PENNSYLVANIA, 16802, USA |
| manuel@psu.edu | |
| Phone | 8148673527 |
| Submit Date | 2021-10-26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-02-16 |
| Release Version | 1 |
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Treatment:
| Treatment ID: | TR002078 |
| Treatment Summary: | In all conditions 1*10^8 cells were cultured in 5 mL of RPMI 1640 media for 2.5 hours. At the start of the incubation period, cells were either not exposed to any drug or exposed to 240 nM, 24 nM, or 2.4 nM MMV693183. Dates reflect date of running an individual sample on the analytical platform. |
| Treatment Compound: | MMV693183 |
| Treatment Route: | Transfer to media by pipette |
| Treatment Dose: | 5 microliters of drug to a final concentration of 240 nM, 24 nM, or 2.4 nM. |
| Treatment Vehicle: | DMSO |
| Cell Growth Container: | 6-well plate |
| Cell Growth Config: | 5 mL in each sample well, 1x10^8 infected red blood cells per well, conditions performed in triplicate |
| Cell Media: | RPMI 1640 containing Albumax, Gentamycin, Hypoxanthine, HEPES, Sodium Bicarbonate |
