Studies involving disease:Neurodegenerative disease

Study ID Study Title Species Institute
ST002825Brain Metabolomics in Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)HumanUniversity of California, Davis
ST003052Synaptic vesicle lipidomics captures signatures of aging and synucleinopathyMouseWeill Cornell Medicine
ST003112Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD PhenotypesMouseThomas Jefferson University
ST003118Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes - Study 2MouseThomas Jefferson University
ST003418Analysis of lipid composition of TLCD1 KO cultured cellsHumanUniversity of Cambridge
ST003419Analysis of lipid composition of the mitochondria isolated from TLCD1 KO cell modelsHumanUniversity of Cambridge
ST003420Analysis of lipid composition of control, YPR114w and YJR116w yeast mutants grown under exponential phaseSaccharomyces cerevisiaeUniversity of Cambridge
ST003424Analysis of lipid composition of HeLa and U2OS CLN8 KO cultured cellsHumanUniversity of Cambridge
ST003875Glia-derived secretory fatty acid binding protein Obp44a regulates lipid storage and efflux in the developing Drosophila brainInsectAdvanced Science Research Center - CUNY
ST004015SLC45A4 encodes a peroxisomal putrescine transporter that promotes GABA de novo synthesisHumanRutgers University
ST004058Targeted Lipid and Metabolite Profiling in ATP13A2 knockout (KO) in HAP1 cellsHumanDenali Therapeutics
ST004059Targeted Lipid and Metabolite Profiling in Brains of ATP13A2 Knockout MiceMouseDenali Therapeutics
ST004070Metabolic perturbation in ependymal cells leads to local and distant neurodegeneration and cognitive decline - Study 1 of 3 (12-month Glut1KO against Ctrl)MouseUniversity of Calgary
ST004071Metabolic perturbation in ependymal cells leads to local and distant neurodegeneration and cognitive decline - Study 2 of 3 (12-month Glut1KO against Ctrl)MouseUniversity of Calgary
ST004072Metabolic perturbation in ependymal cells leads to local and distant neurodegeneration and cognitive decline - Study 3 of 3 (1-month Glut1KO against Ctrl)MouseUniversity of Calgary
ST004097ODC1 overexpression increased the extracellular putrescine concentration in both WT and SLC45A4 KO cellsHumanRutgers University
ST004106Mitochondrial complex III-derived reactive oxygen species amplify immunometabolic changes in astrocytes and promote dementia pathologyMouseWeill Cornell Medicine
ST004205Lipidomic/Metabolomic Characterization of GPR34 KO, WT, TREM2 KO, and GPR34/TREM2 dKO iPSC1-derived microgliaHumanDenali Therapeutics
ST004206Lipidomic Profiling of Sorted Microglia in GPR34-KO/APP-KI Mice Across 4, 8, 16, and 24 MonthsMouseDenali Therapeutics
ST004267Histone deacetylase SIRT6 regulates tryptophan catabolism and prevents metabolite imbalance associated with neurodegeneration - Human cell linesHumanVIB-KU Leuven Center for Cancer Biology
ST004268Histone deacetylase SIRT6 regulates tryptophan catabolism and prevents metabolite imbalance associated with neurodegeneration - DrosophilaFruit flyVIB-KU Leuven Center for Cancer Biology

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