MGP Database

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MGP000163

Ontology/Pathway Information

Entrez Gene ID329
Gene Namebaculoviral IAP repeat containing 2
Gene Symbol BIRC2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0035631 ISS:BHF-UCLCCD40 receptor complex
GO:0009898 ISS:BHF-UCLCcytoplasmic side of plasma membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0005634 IDA:UniProtKBCnucleus
GO:0016874 IEA:UniProtKB-KWFligase activity
GO:0047485 IPI:UniProtKBFprotein N-terminus binding
GO:0003713 IMP:UniProtKBFtranscription coactivator activity
GO:0004842 IDA:UniProtKBFubiquitin-protein transferase activity
GO:0008270 IDA:UniProtKBFzinc ion binding
GO:0006915 TAS:ReactomePapoptotic process
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0006921 TAS:ReactomePcellular component disassembly involved in execution phase of apoptosis
GO:0045087 TAS:ReactomePinnate immune response
GO:0002756 TAS:ReactomePMyD88-independent toll-like receptor signaling pathway
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0038061 TAS:UniProtKBPNIK/NF-kappaB signaling
GO:0043123 IEP:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524 IDA:UniProtKBPpositive regulation of protein K48-linked ubiquitination
GO:1902523 IDA:UniProtKBPpositive regulation of protein K63-linked ubiquitination
GO:1902527 IDA:UniProtKBPpositive regulation of protein monoubiquitination
GO:0043161 IDA:UniProtKBPproteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209 IDA:UniProtKBPprotein polyubiquitination
GO:0042981 IMP:UniProtKBPregulation of apoptotic process
GO:0051726 IDA:UniProtKBPregulation of cell cycle
GO:0045595 TAS:UniProtKBPregulation of cell differentiation
GO:0042127 TAS:UniProtKBPregulation of cell proliferation
GO:2000116 TAS:UniProtKBPregulation of cysteine-type endopeptidase activity
GO:0050727 TAS:UniProtKBPregulation of inflammatory response
GO:0045088 TAS:UniProtKBPregulation of innate immune response
GO:0060544 IMP:UniProtKBPregulation of necroptotic process
GO:0070424 TAS:UniProtKBPregulation of nucleotide-binding oligomerization domain containing signaling pathway
GO:0039535 TAS:UniProtKBPregulation of RIG-I signaling pathway
GO:0034121 TAS:UniProtKBPregulation of toll-like receptor signaling pathway
GO:0006355 IEA:UniProtKB-KWPregulation of transcription, DNA-templated
GO:0034138 TAS:ReactomePtoll-like receptor 3 signaling pathway
GO:0034142 TAS:ReactomePtoll-like receptor 4 signaling pathway
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
GO:0035666 TAS:ReactomePTRIF-dependent toll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6890Activated TLR4 signalling
REACT_578Apoptosis
REACT_107Apoptotic cleavage of cellular proteins
REACT_995Apoptotic execution phase
REACT_25374IKK complex recruitment mediated by RIP1
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_6809MyD88-independent cascade
REACT_75776NOD1/2 Signaling Pathway
REACT_75913Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
REACT_268456Programmed Cell Death
REACT_6783Toll Like Receptor 3 (TLR3) Cascade
REACT_6894Toll Like Receptor 4 (TLR4) Cascade
REACT_6966Toll-Like Receptors Cascades
REACT_25281TRIF-mediated TLR3/TLR4 signaling
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