MGP Database

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MGP000353

Ontology/Pathway Information

Entrez Gene ID717
Gene Namecomplement component 2
Gene Symbol C2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 TAS:ProtIncCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004252 IEA:InterProFserine-type endopeptidase activity
GO:0006956 IMP:BHF-UCLPcomplement activation
GO:0006958 TAS:ProtIncPcomplement activation, classical pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:2000427 IMP:BHF-UCLPpositive regulation of apoptotic cell clearance
GO:0030449 TAS:ReactomePregulation of complement activation
GO:0007584 IEA:EnsemblPresponse to nutrient
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_7972Activation of C3 and C5
REACT_6932Complement cascade
REACT_6900Immune System
REACT_8024Initial triggering of complement
REACT_6802Innate Immune System
REACT_118707Regulation of Complement cascade
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