MGP Database

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MGP000689

UniProt Annotations

Entry Information
Gene Namehyaluronan and proteoglycan link protein 1
Protein EntryHPLN1_HUMAN
UniProt IDP10915
SpeciesHuman
Comments
Comment typeDescription
FunctionStabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
SimilarityBelongs to the HAPLN family. {ECO:0000305}.
SimilarityContains 1 Ig-like V-type (immunoglobulin-like) domain. {ECO:0000305}.
SimilarityContains 2 Link domains. {ECO:0000255|PROSITE- ProRule:PRU00323}.
Subcellular LocationSecreted, extracellular space, extracellular matrix.
Tissue SpecificityWidely expressed. Weakly expressed in the brain. {ECO:0000269|PubMed:11027579, ECO:0000269|PubMed:12663660}.
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