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MGP000939

Ontology/Pathway Information

Entrez Gene ID1975
Gene Nameeukaryotic translation initiation factor 4B
Gene Symbol EIF4B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_2099Cap-dependent Translation Initiation
REACT_20639Deadenylation-dependent mRNA decay
REACT_20514Deadenylation of mRNA
REACT_2159Eukaryotic Translation Initiation
REACT_71Gene Expression
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_150210IGF1R signaling cascade
REACT_1195Insulin receptor signalling cascade
REACT_332IRS-mediated signalling
REACT_762IRS-related events
REACT_150203IRS-related events triggered by IGF1R
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_17015Metabolism of proteins
REACT_6964mTORC1-mediated signalling
REACT_6838mTOR signalling
REACT_976PI3K Cascade
REACT_456PKB-mediated events
REACT_931Ribosomal scanning and start codon recognition
REACT_6754S6K1-mediated signalling
REACT_6772S6K1 signalling
REACT_498Signaling by Insulin receptor
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_111102Signal Transduction
REACT_1014Translation
REACT_1979Translation initiation complex formation
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