MGP Database

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MGP001128

Ontology/Pathway Information

Entrez Gene ID2550
Gene Namegamma-aminobutyric acid (GABA) B receptor, 1
Gene Symbol GABBR1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0005737 IEA:EnsemblCcytoplasm
GO:0030425 IEA:UniProtKB-SubCellCdendrite
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0038039 IPI:UniProtKBCG-protein coupled receptor heterodimeric complex
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0042734 IEA:EnsemblCpresynaptic membrane
GO:0004965 IDA:UniProtKBFG-protein coupled GABA receptor activity
GO:0007193 IDA:UniProtKBPadenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007214 IDA:UniProtKBPgamma-aminobutyric acid signaling pathway
GO:0007194 TAS:ProtIncPnegative regulation of adenylate cyclase activity
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_25330Activation of GABAB receptors
REACT_75831Activation of G protein gated Potassium channels
REACT_18319Class C/3 (Metabotropic glutamate/pheromone receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_25031GABA B receptor activation
REACT_25199GABA receptor activation
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_75780G protein gated Potassium channels
REACT_25004Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
REACT_75918Inwardly rectifying K+ channels
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_75908Potassium Channels
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_13477Transmission across Chemical Synapses
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