MGP Database

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MGP001210

UniProt Annotations

Entry Information
Gene Namegap junction protein, alpha 4, 37kDa
Protein EntryCXA4_HUMAN
UniProt IDP35212
SpeciesHuman
Comments
Comment typeDescription
FunctionOne gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
InteractionP35372:OPRM1; NbExp=2; IntAct=EBI-6918707, EBI-2624570;
SimilarityBelongs to the connexin family. Alpha-type (group II) subfamily. {ECO:0000305}.
Subcellular LocationCell membrane; Multi-pass membrane protein. Cell junction, gap junction.
SubunitA connexon is composed of a hexamer of connexins.
Tissue SpecificityExpressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
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