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MGP001304

Record overview

MGPD IDMGP001304
Gene ID2877
SpeciesHomo sapiens (Human)
Gene Nameglutathione peroxidase 2 (gastrointestinal)
Gene Symbol GPX2
SynonymsGPRP; GPx-2; GI-GPx; GPRP-2; GPx-GI; GSHPx-2; GSHPX-GI;
Alternate namesglutathione peroxidase 2; gastrointestinal glutathione peroxidase; glutathione peroxidase-related protein 2;
Chromosome14
Map Location14q24.1
EC Number1.11.1.9
SummaryThis gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
OrthologsView orthologs and multiple alignments for GPX2

Proteins

glutathione peroxidase 2
Refseq ID:NP_002074
Protein GI:32967607
UniProt ID:P18283
mRNA ID:NM_002083
Length:190
RefSeq Status:
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFT
LVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
 
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