MGP Database

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MGP001435

Ontology/Pathway Information

Entrez Gene ID3082
Gene Namehepatocyte growth factor (hepapoietin A; scatter factor)
Gene Symbol HGF
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IEA:EnsemblCextracellular space
GO:0016020 IDA:UniProtKBCmembrane
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0003824 IEA:InterProFcatalytic activity
GO:0042056 IDA:BHF-UCLFchemoattractant activity
GO:0008083 NAS:UniProtKBFgrowth factor activity
GO:0042802 IPI:IntActFidentical protein binding
GO:0000187 IEA:EnsemblPactivation of MAPK activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0060326 IDA:BHF-UCLPcell chemotaxis
GO:0035729 IDA:BHF-UCLPcellular response to hepatocyte growth factor stimulus
GO:0001837 TAS:HGNCPepithelial to mesenchymal transition
GO:0048012 IDA:BHF-UCLPhepatocyte growth factor receptor signaling pathway
GO:0030212 IEA:EnsemblPhyaluronan metabolic process
GO:0001889 IEA:EnsemblPliver development
GO:0007067 NAS:UniProtKBPmitotic nuclear division
GO:0051450 IEA:EnsemblPmyoblast proliferation
GO:0043154 IDA:BHF-UCLPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:1902042 IEA:EnsemblPnegative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901299 IDA:BHF-UCLPnegative regulation of hydrogen peroxide-mediated programmed cell death
GO:0090201 IDA:BHF-UCLPnegative regulation of release of cytochrome c from mitochondria
GO:0031100 IEA:EnsemblPorgan regeneration
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0050918 IDA:GOCPpositive chemotaxis
GO:0045766 IEA:EnsemblPpositive regulation of angiogenesis
GO:0030335 IDA:BHF-UCLPpositive regulation of cell migration
GO:2000573 IDA:UniProtKBPpositive regulation of DNA biosynthetic process
GO:0031643 IEA:EnsemblPpositive regulation of myelination
GO:0070572 IEA:EnsemblPpositive regulation of neuron projection regeneration
GO:0045669 NAS:BHF-UCLPpositive regulation of osteoblast differentiation
GO:0050731 IDA:BHF-UCLPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0014068 IDA:BHF-UCLPpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0045944 NAS:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0060665 IDA:MGIPregulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_604Hemostasis
REACT_6900Immune System
REACT_115529Interleukin-7 signaling
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_22232Signaling by Interleukins
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