MGP Database

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MGP001499

Ontology/Pathway Information

Entrez Gene ID3273
Gene Namehistidine-rich glycoprotein
Gene Symbol HRG
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0072562 IDA:UniProtKBCblood microparticle
GO:0036019 IEA:EnsemblCendolysosome
GO:0005576 IDA:UniProtKBCextracellular region
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0061474 IEA:EnsemblCphagolysosome membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0004869 IEA:InterProFcysteine-type endopeptidase inhibitor activity
GO:0020037 IDA:UniProtKBFheme binding
GO:0043395 IDA:UniProtKBFheparan sulfate proteoglycan binding
GO:0008201 IDA:UniProtKBFheparin binding
GO:0019865 IDA:UniProtKBFimmunoglobulin binding
GO:0046872 IDA:UniProtKBFmetal ion binding
GO:0005102 IDA:UniProtKBFreceptor binding
GO:0004867 IEA:EnsemblFserine-type endopeptidase inhibitor activity
GO:0008270 IDA:UniProtKBFzinc ion binding
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0007596 TAS:ReactomePblood coagulation
GO:0006935 IEA:UniProtKB-KWPchemotaxis
GO:0050832 IDA:UniProtKBPdefense response to fungus
GO:0042730 TAS:ReactomePfibrinolysis
GO:0097037 IEA:EnsemblPheme export
GO:0016525 IDA:UniProtKBPnegative regulation of angiogenesis
GO:0043537 ISS:UniProtKBPnegative regulation of blood vessel endothelial cell migration
GO:0007162 IDA:UniProtKBPnegative regulation of cell adhesion
GO:0033629 IDA:UniProtKBPnegative regulation of cell adhesion mediated by integrin
GO:0030308 IDA:UniProtKBPnegative regulation of cell growth
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:2001027 IDA:UniProtKBPnegative regulation of endothelial cell chemotaxis
GO:0051918 IEA:EnsemblPnegative regulation of fibrinolysis
GO:0010593 IDA:UniProtKBPnegative regulation of lamellipodium assembly
GO:1900747 IDA:UniProtKBPnegative regulation of vascular endothelial growth factor signaling pathway
GO:0030168 IDA:UniProtKBPplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0043065 IDA:UniProtKBPpositive regulation of apoptotic process
GO:2000504 IDA:UniProtKBPpositive regulation of blood vessel remodeling
GO:0051894 IDA:UniProtKBPpositive regulation of focal adhesion assembly
GO:0002839 IDA:UniProtKBPpositive regulation of immune response to tumor cell
GO:0032956 IDA:UniProtKBPregulation of actin cytoskeleton organization
GO:0030193 IDA:UniProtKBPregulation of blood coagulation
GO:0010468 IDA:UniProtKBPregulation of gene expression
GO:0050730 IDA:UniProtKBPregulation of peptidyl-tyrosine phosphorylation
GO:0010543 ISS:UniProtKBPregulation of platelet activation
GO:0043254 IDA:UniProtKBPregulation of protein complex assembly
GO:0034395 IEA:EnsemblPregulation of transcription from RNA polymerase II promoter in response to iron
GO:0014070 IEA:EnsemblPresponse to organic cyclic compound
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_641Dissolution of Fibrin Clot
REACT_604Hemostasis
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_1280Response to elevated platelet cytosolic Ca2+
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