MGP Database

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MGP001510

Ontology/Pathway Information

Entrez Gene ID3295
Gene Namehydroxysteroid (17-beta) dehydrogenase 4
Gene Symbol HSD17B4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005782 TAS:ReactomeCperoxisomal matrix
GO:0005778 IDA:UniProtKBCperoxisomal membrane
GO:0005777 IDA:UniProtKBCperoxisome
GO:0044594 IDA:UniProtKBF17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0033989 TAS:ReactomeF3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
GO:0003857 IDA:UniProtKBF3-hydroxyacyl-CoA dehydrogenase activity
GO:0016853 IEA:UniProtKB-KWFisomerase activity
GO:0016508 IDA:UniProtKBFlong-chain-enoyl-CoA hydratase activity
GO:0042803 IDA:UniProtKBFprotein homodimerization activity
GO:0005102 IPI:UniProtKBFreceptor binding
GO:0036109 TAS:ReactomePalpha-linolenic acid metabolic process
GO:0008209 IDA:UniProtKBPandrogen metabolic process
GO:0006699 TAS:ReactomePbile acid biosynthetic process
GO:0008206 TAS:ReactomePbile acid metabolic process
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0008210 IDA:UniProtKBPestrogen metabolic process
GO:0006635 IDA:UniProtKBPfatty acid beta-oxidation
GO:0033540 TAS:ReactomePfatty acid beta-oxidation using acyl-CoA oxidase
GO:0036112 IDA:UniProtKBPmedium-chain fatty-acyl-CoA metabolic process
GO:0008152 IDA:GOCPmetabolic process
GO:0001649 IDA:UniProtKBPosteoblast differentiation
GO:0055114 IDA:GOCPoxidation-reduction process
GO:0060009 IEA:EnsemblPSertoli cell development
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0033559 TAS:ReactomePunsaturated fatty acid metabolic process
GO:0000038 IEA:EnsemblPvery long-chain fatty acid metabolic process
GO:0036111 IDA:UniProtKBPvery long-chain fatty-acyl-CoA metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121147alpha-linolenic acid (ALA) metabolism
REACT_121284alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
REACT_17017Beta-oxidation of pristanoyl-CoA
REACT_17062Beta-oxidation of very long chain fatty acids
REACT_11040Bile acid and bile salt metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_16957Peroxisomal lipid metabolism
REACT_11054Synthesis of bile acids and bile salts
REACT_11041Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
SMP Pathway Links
SMP IDDescription
SMP0072027-Hydroxylase Deficiency
SMP00035Bile Acid Biosynthesis
SMP00315Cerebrotendinous Xanthomatosis (CTX)
SMP00314Congenital Bile Acid Synthesis Defect Type II
SMP00318Congenital Bile Acid Synthesis Defect Type III
SMP00317Familial Hypercholanemia (FHCA)
SMP00316Zellweger Syndrome
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