MGP Database

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MGP001511

Ontology/Pathway Information

Entrez Gene ID3297
Gene Nameheat shock transcription factor 1
Gene Symbol HSF1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005654 IDA:HPACnucleoplasm
GO:0045120 IEA:EnsemblCpronucleus
GO:0043234 IEA:EnsemblCprotein complex
GO:0003682 IEA:EnsemblFchromatin binding
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001162 IDA:MGIFRNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
GO:0003700 TAS:ProtIncFsequence-specific DNA binding transcription factor activity
GO:0034605 IDA:UniProtKBPcellular response to heat
GO:0006952 IEA:EnsemblPdefense response
GO:0001892 IEA:EnsemblPembryonic placenta development
GO:0060136 IEA:EnsemblPembryonic process involved in female pregnancy
GO:0007143 IEA:EnsemblPfemale meiotic division
GO:0008285 IEA:EnsemblPnegative regulation of cell proliferation
GO:0000122 IDA:NTNU_SBPnegative regulation of transcription from RNA polymerase II promoter
GO:0032720 IEA:EnsemblPnegative regulation of tumor necrosis factor production
GO:0040018 IEA:EnsemblPpositive regulation of multicellular organism growth
GO:0045944 IDA:MGIPpositive regulation of transcription from RNA polymerase II promoter
GO:0006468 IEA:EnsemblPprotein phosphorylation
GO:0090231 IEA:EnsemblPregulation of spindle checkpoint
GO:0032496 IEA:EnsemblPresponse to lipopolysaccharide
GO:0007283 IEA:EnsemblPspermatogenesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264075Attenuation phase
REACT_120956Cellular responses to stress
REACT_263897Cellular response to heat stress
REACT_264071HSF1 activation
REACT_264164HSF1-dependent transactivation
REACT_264487Regulation of HSF1-mediated heat shock response
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