MGP Database

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MGP001638

Ontology/Pathway Information

Entrez Gene ID3635
Gene Nameinositol polyphosphate-5-phosphatase, 145kDa
Gene Symbol INPP5D
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 IEA:UniProtKB-SubCellCmembrane
GO:0004445 TAS:ProtIncFinositol-polyphosphate 5-phosphatase activity
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0007596 TAS:ReactomePblood coagulation
GO:0043647 TAS:ReactomePinositol phosphate metabolic process
GO:0050900 TAS:ReactomePleukocyte migration
GO:0006796 TAS:ProtIncPphosphate-containing compound metabolic process
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0046856 IEA:InterProPphosphatidylinositol dephosphorylation
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0007165 TAS:ProtIncPsignal transduction
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_12051Cell surface interactions at the vascular wall
REACT_75790Cytokine Signaling in Immune system
REACT_12555Downstream TCR signaling
REACT_604Hemostasis
REACT_6900Immune System
REACT_150154Inositol phosphate metabolism
REACT_27283Interleukin-2 signaling
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_23891Interleukin receptor SHC signaling
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_12519PECAM1 interactions
REACT_120870Phospholipid metabolism
REACT_121175PI Metabolism
REACT_22232Signaling by Interleukins
REACT_150312Synthesis of IP3 and IP4 in the cytosol
REACT_121025Synthesis of PIPs at the plasma membrane
REACT_12526TCR signaling
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
SMP00582Joubert syndrome
SMP00463Phosphatidylinositol Phosphate Metabolism
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