MGP Database

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MGP001652

Ontology/Pathway Information

Entrez Gene ID3662
Gene Nameinterferon regulatory factor 4
Gene Symbol IRF4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 IDA:UniProtKBCmembrane
GO:0000788 IEA:EnsemblCnuclear nucleosome
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IC:UniProtKBCnucleus
GO:0016279 IEA:EnsemblFprotein-lysine N-methyltransferase activity
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0043565 ISS:UniProtKBFsequence-specific DNA binding
GO:0003700 ISS:UniProtKBFsequence-specific DNA binding transcription factor activity
GO:0008134 NAS:UniProtKBFtranscription factor binding
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0042832 ISS:UniProtKBPdefense response to protozoan
GO:0043966 IEA:EnsemblPhistone H3 acetylation
GO:0043967 IEA:EnsemblPhistone H4 acetylation
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0043011 IEA:EnsemblPmyeloid dendritic cell differentiation
GO:0034122 IEA:EnsemblPnegative regulation of toll-like receptor signaling pathway
GO:0043388 IEA:EnsemblPpositive regulation of DNA binding
GO:0045082 IDA:UniProtKBPpositive regulation of interleukin-10 biosynthetic process
GO:0045368 IDA:UniProtKBPpositive regulation of interleukin-13 biosynthetic process
GO:0045086 IDA:UniProtKBPpositive regulation of interleukin-2 biosynthetic process
GO:0045404 IDA:UniProtKBPpositive regulation of interleukin-4 biosynthetic process
GO:0045893 IDA:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:NTNU_SBPpositive regulation of transcription from RNA polymerase II promoter
GO:0045622 NAS:UniProtKBPregulation of T-helper cell differentiation
GO:0042110 NAS:UniProtKBPT cell activation
GO:0072540 ISS:UniProtKBPT-helper 17 cell lineage commitment
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25162Interferon alpha/beta signaling
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
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