MGP Database

MGP001869

Ontology/Pathway Information

Entrez Gene ID	4137
Gene Name	microtubule-associated protein tau
Gene Symbol	MAPT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0030424	IDA:UniProtKB	C	axon
GO:0005930	IEA:Ensembl	C	axoneme
GO:0036464	IDA:ParkinsonsUK-UCL	C	cytoplasmic ribonucleoprotein granule
GO:0005829	TAS:Reactome	C	cytosol
GO:0030426	IDA:UniProtKB	C	growth cone
GO:0005874	IEA:UniProtKB-KW	C	microtubule
GO:0005875	TAS:ProtInc	C	microtubule associated complex
GO:0034399	IDA:UniProtKB	C	nuclear periphery
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0045298	IDA:UniProtKB	C	tubulin complex
GO:0034185	IPI:BHF-UCL	F	apolipoprotein binding
GO:0019899	IPI:UniProtKB	F	enzyme binding
GO:0071813	IPI:UniProtKB	F	lipoprotein particle binding
GO:0008017	IDA:UniProtKB	F	microtubule binding
GO:0017124	IPI:UniProtKB	F	SH3 domain binding
GO:0005200	TAS:ProtInc	F	structural constituent of cytoskeleton
GO:0007628	IEA:Ensembl	P	adult walking behavior
GO:0006915	TAS:Reactome	P	apoptotic process
GO:0008088	IEA:Ensembl	P	axon cargo transport
GO:0048675	IEA:Ensembl	P	axon extension
GO:0006921	TAS:Reactome	P	cellular component disassembly involved in execution phase of apoptosis
GO:0048699	NAS:UniProtKB	P	generation of neurons
GO:0000226	IDA:UniProtKB	P	microtubule cytoskeleton organization
GO:0047497	IEA:Ensembl	P	mitochondrion transport along microtubule
GO:0032387	IEA:Ensembl	P	negative regulation of intracellular transport
GO:0001764	IEA:Ensembl	P	neuron migration
GO:0045773	IDA:UniProtKB	P	positive regulation of axon extension
GO:0031116	IDA:UniProtKB	P	positive regulation of microtubule polymerization
GO:0010506	IGI:MGI	P	regulation of autophagy
GO:0060632	IEA:Ensembl	P	regulation of microtubule-based movement
GO:0031113	NAS:UniProtKB	P	regulation of microtubule polymerization

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_578	Apoptosis
REACT_107	Apoptotic cleavage of cellular proteins
REACT_995	Apoptotic execution phase
REACT_13541	Caspase-mediated cleavage of cytoskeletal proteins
REACT_268456	Programmed Cell Death