MGP Database

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MGP001879

Ontology/Pathway Information

Entrez Gene ID4158
Gene Namemelanocortin 2 receptor (adrenocorticotropic hormone)
Gene Symbol MC2R
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IEA:EnsemblCcytoplasm
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004978 TAS:ProtIncFcorticotropin receptor activity
GO:0004977 TAS:ProtIncFmelanocortin receptor activity
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007218 TAS:GOCPneuropeptide signaling pathway
GO:0001890 IEA:EnsemblPplacenta development
GO:0030819 IDA:BHF-UCLPpositive regulation of cAMP biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00310Corticotropin Activation of Cortisol Production
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