MGP Database

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MGP001937

Ontology/Pathway Information

Entrez Gene ID4314
Gene Namematrix metallopeptidase 3 (stromelysin 1, progelatinase)
Gene Symbol MMP3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 TAS:ProtIncCextracellular space
GO:0005578 IEA:UniProtKB-SubCellCproteinaceous extracellular matrix
GO:0005509 IEA:InterProFcalcium ion binding
GO:0004175 IDA:ParkinsonsUK-UCLFendopeptidase activity
GO:0004222 TAS:ProtIncFmetalloendopeptidase activity
GO:0008270 IEA:InterProFzinc ion binding
GO:0071230 IEA:EnsemblPcellular response to amino acid stimulus
GO:0071732 TAS:ParkinsonsUK-UCLPcellular response to nitric oxide
GO:0030574 TAS:ReactomePcollagen catabolic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0010727 IDA:ParkinsonsUK-UCLPnegative regulation of hydrogen peroxide metabolic process
GO:1903209 ISS:ParkinsonsUK-UCLPpositive regulation of oxidative stress-induced cell death
GO:0032461 IDA:ParkinsonsUK-UCLPpositive regulation of protein oligomerization
GO:0006508 IDA:UniProtKBPproteolysis
GO:0030334 IEA:EnsemblPregulation of cell migration
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_150401Collagen degradation
REACT_120729Collagen formation
REACT_118572Degradation of the extracellular matrix
REACT_121096EGFR Transactivation by Gastrin
REACT_118779Extracellular matrix organization
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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