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MGP001974

UniProt Annotations

Entry Information
Gene Namemelatonin receptor 1B
Protein EntryMTR1B_HUMAN
UniProt IDP49286
SpeciesHuman
Comments
Comment typeDescription
FunctionHigh affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
InteractionP48039:MTNR1A; NbExp=2; IntAct=EBI-1188341, EBI-1188238; O76081:RGS20; NbExp=2; IntAct=EBI-1188341, EBI-1052678;
SimilarityBelongs to the G-protein coupled receptor 1 family. {ECO:0000255|PROSITE-ProRule:PRU00521}.
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in retina and less in brain and hippocampus.
Web ResourceName=Wikipedia; Note=Melatonin receptor entry; URL="http://en.wikipedia.org/wiki/Melatonin_receptor";
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