MGP Database

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MGP002042

UniProt Annotations

Entry Information
Gene NameNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
Protein Entry
UniProt ID
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q16718-1; Sequence=Displayed; Name=2; IsoId=Q16718-2; Sequence=VSP_055164; Note=No experimental confirmation available.;
FunctionAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
SimilarityBelongs to the complex I NDUFA5 subunit family. {ECO:0000305}.
Subcellular LocationMitochondrion inner membrane; Peripheral membrane protein; Matrix side.
SubunitComplex I is composed of 45 different subunits. {ECO:0000269|PubMed:12611891}.
Tissue SpecificityExpressed in all tissues examined with highest levels in heart, skeletal muscle and brain.
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