MGP Database

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MGP002062

Ontology/Pathway Information

Entrez Gene ID4719
Gene NameNADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Gene Symbol NDUFS1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005743 TAS:ReactomeCmitochondrial inner membrane
GO:0005758 IDA:UniProtKBCmitochondrial intermembrane space
GO:0005747 IDA:UniProtKBCmitochondrial respiratory chain complex I
GO:0005739 IDA:HPACmitochondrion
GO:0051537 IEA:UniProtKB-KWF2 iron, 2 sulfur cluster binding
GO:0051539 IEA:UniProtKB-KWF4 iron, 4 sulfur cluster binding
GO:0009055 NAS:UniProtKBFelectron carrier activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008137 NAS:UniProtKBFNADH dehydrogenase (ubiquinone) activity
GO:0008637 IDA:UniProtKBPapoptotic mitochondrial changes
GO:0046034 IMP:UniProtKBPATP metabolic process
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0045333 IMP:UniProtKBPcellular respiration
GO:0006120 NAS:UniProtKBPmitochondrial electron transport, NADH to ubiquinone
GO:0072593 IMP:UniProtKBPreactive oxygen species metabolic process
GO:0051881 IMP:UniProtKBPregulation of mitochondrial membrane potential
GO:0022904 TAS:ReactomePrespiratory electron transport chain
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_22393Respiratory electron transport
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
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