MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002233

Ontology/Pathway Information

Entrez Gene ID5166
Gene Namepyruvate dehydrogenase kinase, isozyme 4
Gene Symbol PDK4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005743 IEA:EnsemblCmitochondrial inner membrane
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 TAS:ProtIncCmitochondrion
GO:0005524 IDA:UniProtKBFATP binding
GO:0004672 IDA:UniProtKBFprotein kinase activity
GO:0004740 ISS:UniProtKBFpyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0071398 IMP:UniProtKBPcellular response to fatty acid
GO:0009267 IDA:UniProtKBPcellular response to starvation
GO:0042593 ISS:UniProtKBPglucose homeostasis
GO:0006006 IEA:UniProtKB-KWPglucose metabolic process
GO:0008286 IMP:UniProtKBPinsulin receptor signaling pathway
GO:2000811 IMP:UniProtKBPnegative regulation of anoikis
GO:0006468 IDA:GOCPprotein phosphorylation
GO:0006090 TAS:ReactomePpyruvate metabolic process
GO:0072593 IMP:UniProtKBPreactive oxygen species metabolic process
GO:0010510 IMP:UniProtKBPregulation of acetyl-CoA biosynthetic process from pyruvate
GO:0045124 IEA:EnsemblPregulation of bone resorption
GO:0010565 ISS:UniProtKBPregulation of cellular ketone metabolic process
GO:0042304 IMP:UniProtKBPregulation of fatty acid biosynthetic process
GO:0046320 ISS:UniProtKBPregulation of fatty acid oxidation
GO:0010906 IMP:UniProtKBPregulation of glucose metabolic process
GO:0006885 ISS:UniProtKBPregulation of pH
GO:0042594 ISS:UniProtKBPresponse to starvation
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_2071Pyruvate metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_12528Regulation of pyruvate dehydrogenase (PDH) complex
REACT_267785Signaling by Retinoic Acid
REACT_111102Signal Transduction
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
  logo