MGP Database

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MGP002412

Ontology/Pathway Information

Entrez Gene ID5557
Gene Nameprimase, DNA, polypeptide 1 (49kDa)
Gene Symbol PRIM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016020 IDA:UniProtKBCmembrane
GO:0005654 TAS:ReactomeCnucleoplasm
GO:1990077 IEA:UniProtKB-KWCprimosome complex
GO:0003896 TAS:ProtIncFDNA primase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0006270 TAS:ReactomePDNA replication initiation
GO:0006269 TAS:ProtIncPDNA replication, synthesis of RNA primer
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0000723 TAS:ReactomePtelomere maintenance
GO:0000722 TAS:ReactomePtelomere maintenance via recombination
GO:0032201 TAS:ReactomePtelomere maintenance via semi-conservative replication
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1095Activation of the pre-replicative complex
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_22172Chromosome Maintenance
REACT_383DNA Replication
REACT_2244DNA replication initiation
REACT_734DNA Replication Pre-Initiation
REACT_932DNA strand elongation
REACT_471E2F mediated regulation of DNA replication
REACT_8030Extension of Telomeres
REACT_1783G1/S Transition
REACT_329Inhibition of replication initiation of damaged DNA by RB1/E2F1
REACT_312Lagging Strand Synthesis
REACT_1838Leading Strand Synthesis
REACT_1725M/G1 Transition
REACT_21267Mitotic G1-G1/S phases
REACT_1792Polymerase switching
REACT_7987Polymerase switching on the C-strand of the telomere
REACT_1385Processive synthesis on the lagging strand
REACT_70Removal of the Flap Intermediate
REACT_899S Phase
REACT_2014Synthesis of DNA
REACT_7961Telomere C-strand (Lagging Strand) Synthesis
REACT_7993Telomere C-strand synthesis initiation
REACT_7970Telomere Maintenance
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