MGP Database

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MGP002458

Ontology/Pathway Information

Entrez Gene ID5631
Gene Namephosphoribosyl pyrophosphate synthetase 1
Gene Symbol PRPS1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005524 IDA:UniProtKBFATP binding
GO:0016301 IEA:UniProtKB-KWFkinase activity
GO:0000287 IEA:InterProFmagnesium ion binding
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0004749 IDA:UniProtKBFribose phosphate diphosphokinase activity
GO:0006015 TAS:ReactomeP5-phosphoribose 1-diphosphate biosynthetic process
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0046101 IMP:UniProtKBPhypoxanthine biosynthetic process
GO:0007399 IMP:UniProtKBPnervous system development
GO:0006144 IMP:UniProtKBPpurine nucleobase metabolic process
GO:0006164 IMP:UniProtKBPpurine nucleotide biosynthetic process
GO:0006221 NAS:UniProtKBPpyrimidine nucleotide biosynthetic process
GO:0009156 IEA:InterProPribonucleoside monophosphate biosynthetic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0034418 IMP:UniProtKBPurate biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_8505-Phosphoribose 1-diphosphate biosynthesis
REACT_116125Disease
REACT_264090Glycogen storage diseases
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_264430Myoclonic epilepsy of Lafora
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