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MGP002851

UniProt Annotations

Entry Information
Gene Namesolute carrier family 1 (glutamate transporter), member 7
Protein EntryEAA5_HUMAN
UniProt IDO00341
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00341-1; Sequence=Displayed; Name=2; IsoId=O00341-2; Sequence=VSP_056560, VSP_056561; Note=No experimental confirmation available.;
FunctionTransports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
SimilarityBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A7 subfamily. {ECO:0000305}.
Subcellular LocationMembrane; Multi-pass membrane protein.
SubunitInteracts with the PDZ domains of DLG4.
Tissue SpecificityExpressed primarily in retina. Detectable in liver, heart, muscle and brain.
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