MGP Database

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MGP002932

UniProt Annotations

Entry Information
Gene Namesmall nuclear RNA activating complex, polypeptide 1, 43kDa
Protein EntrySNPC1_HUMAN
UniProt IDQ16533
SpeciesHuman
Comments
Comment typeDescription
FunctionPart of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. {ECO:0000269|PubMed:12621023}.
Subcellular LocationNucleus.
SubunitPart of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC1 interacts with SNAPC3, SNAPC4 and TBP. {ECO:0000269|PubMed:11056176, ECO:0000269|PubMed:12621023}.
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