MGP Database

MGP003024

Record overview

MGPD ID	MGP003024
Gene ID	6821
Species	Homo sapiens (Human)
Gene Name	sulfite oxidase
Gene Symbol	SUOX
Alternate names	sulfite oxidase, mitochondrial;
Chromosome	12
Map Location	12q13.2
EC Number	1.8.3.1
Summary	Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for SUOX

Proteins

sulfite oxidase, mitochondrial

Refseq ID:	NP_000447
Protein GI:	74099694
UniProt ID:	P51687
mRNA ID:	NM_000456
Length:	545
RefSeq Status:

MLLLHRAVVLRLQQACRLKSIPSRICIQACSTNDSFQPQRPSLTFSGDNSSTQGWRVMGTLLGLGAVLAYQDHRCRAAQESTHIYTKEEVSSHTSPETGI
WVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYKIGELNPEDKVAPTVETSDPYADDPVRHPALKVNSQRPFNAEPPP
ELLTENYITPNPIFFTRNHLPVPNLDPDTYRLHVVGAPGGQSLSLSLDDLHNFPRYEITVTLQCAGNRRSEMTQVKEVKGLEWRTGAISTARWAGARLCD
VLAQAGHQLCETEAHVCFEGLDSDPTGTAYGASIPLARAMDPEAEVLLAYEMNGQPLPRDHGFPVRVVVPGVVGARHVKWLGRVSVQPEESYSHWQRRDY
KGFSPSVDWETVDFDSAPSIQELPVQSAITEPRDGETVESGEVTIKGYAWSGGGRAVIRVDVSLDGGLTWQVAKLDGEEQRPRKAWAWRLWQLKAPVPAG
QKELNIVCKAVDDGYNVQPDTVAPIWNLRGVLSNAWHRVHVYVSP

sulfite oxidase, mitochondrial

Refseq ID:	NP_001027559
Protein GI:	74099704
UniProt ID:	P51687
mRNA ID:	NM_001032387
Length:	545
RefSeq Status:

sulfite oxidase, mitochondrial
Protein sequence is identical to GI:74099694 (mRNA isoform)

Refseq ID:	NP_001027558
Protein GI:	74099702
UniProt ID:	P51687
mRNA ID:	NM_001032386
Length:	545
RefSeq Status:

Protein sequence is identical to GI:74099694 (mRNA isoform)