MGP Database

MGP003026

Record overview

MGPD IDMGP003026
Gene ID6827
SpeciesHomo sapiens (Human)
Gene Namesuppressor of Ty 4 homolog 1 (S. cerevisiae)
Gene Symbol SUPT4H1
SynonymsSPT4; SPT4H; SUPT4H;
Alternate namestranscription elongation factor SPT4; DRB sensitivity-inducing factor 14 kDa subunit; DSIF p14; small hSpt4 subunit;
Chromosome17
Map Location17q22
SummaryThis gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
OrthologsView orthologs and multiple alignments for SUPT4H1

Proteins

transcription elongation factor SPT4
Refseq ID:NP_003159
Protein GI:4507311
UniProt ID:P63272
mRNA ID:NM_003168
Length:117
RefSeq Status:
MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPEDSWVSKWQRVSNFKPGVYAVSVTGRLPQGIVRE
LKSRGVAYKSRDTAIKT
 
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