MGP Database

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MGP003204

Ontology/Pathway Information

Entrez Gene ID7225
Gene Nametransient receptor potential cation channel, subfamily C, member 6
Gene Symbol TRPC6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005886 IDA:MGICplasma membrane
GO:0036057 IEA:EnsemblCslit diaphragm
GO:0070679 IDA:BHF-UCLFinositol 1,4,5 trisphosphate binding
GO:0015279 IEA:EnsemblFstore-operated calcium channel activity
GO:0007568 IEA:EnsemblPaging
GO:0007411 TAS:ReactomePaxon guidance
GO:0007596 TAS:ReactomePblood coagulation
GO:0070588 TAS:ReactomePcalcium ion transmembrane transport
GO:0006812 TAS:ProtIncPcation transport
GO:0070301 IEA:EnsemblPcellular response to hydrogen peroxide
GO:0071456 IEA:EnsemblPcellular response to hypoxia
GO:0034220 TAS:ReactomePion transmembrane transport
GO:0030168 TAS:ReactomePplatelet activation
GO:0051928 IDA:MGIPpositive regulation of calcium ion transport
GO:0007204 IEA:EnsemblPpositive regulation of cytosolic calcium ion concentration
GO:0032414 IDA:MGIPpositive regulation of ion transmembrane transporter activity
GO:0055085 TAS:ReactomePtransmembrane transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_2202Effects of PIP2 hydrolysis
REACT_162Elevation of cytosolic Ca2+ levels
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_25300Ion channel transport
REACT_22237Netrin-1 signaling
REACT_798Platelet activation, signaling and aggregation
REACT_23905Platelet calcium homeostasis
REACT_23876Platelet homeostasis
REACT_22228Role of second messengers in netrin-1 signaling
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_160189Stimuli-sensing channels
REACT_15518Transmembrane transport of small molecules
REACT_169333TRP channels
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