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MGP003246

Record overview

MGPD IDMGP003246
Gene ID7326
SpeciesHomo sapiens (Human)
Gene Nameubiquitin-conjugating enzyme E2G 1
Gene Symbol UBE2G1
SynonymsUBC7; E217K; UBE2G;
Alternate namesubiquitin-conjugating enzyme E2 G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); ubiquitin-protein ligase G1;
Chromosome17
Map Location17p13.2
EC Number6.3.2.19
SummaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for UBE2G1

Proteins

ubiquitin-conjugating enzyme E2 G1
Refseq ID:NP_003333
Protein GI:13489085
UniProt ID:P62253
mRNA ID:NM_003342
Length:170
RefSeq Status:
MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGED
KYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE
 
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