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MGP003283

UniProt Annotations

Entry Information
Gene Namevalyl-tRNA synthetase
Protein EntrySYVC_HUMAN
UniProt IDP26640
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P26640-1; Sequence=Displayed; Name=2; IsoId=P26640-2; Sequence=VSP_056480, VSP_056481, VSP_056482; Note=No experimental confirmation available.;
Catalytic ActivityATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val).
Enzyme RegulationCan be regulated by protein kinase C-dependent phosphorylation.
InteractionQ05639:EEF1A2; NbExp=1; IntAct=EBI-355765, EBI-354943; P11171:EPB41; NbExp=1; IntAct=EBI-355765, EBI-1050906; P30480:HLA-B; NbExp=1; IntAct=EBI-355765, EBI-1054175; P19532:TFE3; NbExp=1; IntAct=EBI-355765, EBI-1048957; Q9Y4K3:TRAF6; NbExp=1; IntAct=EBI-355765, EBI-359276;
Sequence CautionSequence=CAA41990.1; Type=Frameshift; Positions=620, 640; Evidence={ECO:0000305};
SimilarityBelongs to the class-I aminoacyl-tRNA synthetase family. {ECO:0000305}.
SimilarityContains 1 GST C-terminal domain. {ECO:0000305}.
SubunitForms high-molecular-mass aggregates with elongation factor 1.
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