MGP Database

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MGP003541

Ontology/Pathway Information

Entrez Gene ID8395
Gene Namephosphatidylinositol-4-phosphate 5-kinase, type I, beta
Gene Symbol PIP5K1B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0012505 IEA:UniProtKB-SubCellCendomembrane system
GO:0016020 IEA:UniProtKB-KWCmembrane
GO:0001931 IDA:UniProtKBCuropod
GO:0016308 NAS:UniProtKBF1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0046854 NAS:GOCPphosphatidylinositol phosphorylation
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_264594misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
REACT_120870Phospholipid metabolism
REACT_121175PI Metabolism
REACT_264378RNF mutants show enhanced WNT signaling and proliferation
REACT_11045Signaling by Wnt
REACT_264125Signaling by WNT in cancer
REACT_111102Signal Transduction
REACT_121025Synthesis of PIPs at the plasma membrane
REACT_264596TCF dependent signaling in response to WNT
REACT_264384WNT mediated activation of DVL
REACT_264356XAV939 inhibits tankyrase, stabilizing AXIN
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