MGP Database

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MGP003771

Ontology/Pathway Information

Entrez Gene ID9023
Gene Namecholesterol 25-hydroxylase
Gene Symbol CH25H
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0001567 IEA:UniProtKB-ECFcholesterol 25-hydroxylase activity
GO:0005506 IEA:InterProFiron ion binding
GO:0008395 TAS:ReactomeFsteroid hydroxylase activity
GO:0006699 TAS:ReactomePbile acid biosynthetic process
GO:0008206 TAS:ReactomePbile acid metabolic process
GO:0008203 IEA:EnsemblPcholesterol metabolic process
GO:0006633 IEA:InterProPfatty acid biosynthetic process
GO:0006629 TAS:ProtIncPlipid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0016126 IEA:UniProtKB-KWPsterol biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11040Bile acid and bile salt metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11054Synthesis of bile acids and bile salts
SMP Pathway Links
SMP IDDescription
SMP0072027-Hydroxylase Deficiency
SMP00035Bile Acid Biosynthesis
SMP00315Cerebrotendinous Xanthomatosis (CTX)
SMP00314Congenital Bile Acid Synthesis Defect Type II
SMP00318Congenital Bile Acid Synthesis Defect Type III
SMP00317Familial Hypercholanemia (FHCA)
SMP00316Zellweger Syndrome
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