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MGP003820

Record overview

MGPD IDMGP003820
Gene ID9170
SpeciesHomo sapiens (Human)
Gene Namelysophosphatidic acid receptor 2
Gene Symbol LPAR2
SynonymsEDG4; LPA2; EDG-4; LPA-2;
Alternate nameslysophosphatidic acid receptor 2; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; lysophosphatidic acid receptor EDG4; lysophosphatidic acid receptor Edg-4;
Chromosome19
Map Location19p12
SummaryThis gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for LPAR2

Proteins

lysophosphatidic acid receptor 2
Refseq ID:NP_004711
Protein GI:7305013
UniProt ID:Q9HBW0
mRNA ID:NM_004720
Length:351
RefSeq Status:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLS
LEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLV
FLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
 
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