MGP Database

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MGP004014

Record overview

MGPD IDMGP004014
Gene ID9801
SpeciesHomo sapiens (Human)
Gene Namemitochondrial ribosomal protein L19
Gene Symbol MRPL19
SynonymsRLX1; L19mt; MRPL15; RPML15; MRP-L15; MRP-L19;
Alternate names39S ribosomal protein L19, mitochondrial; 39S ribosomal protein L15, mitochondrial; L15mt;
Chromosome2
Map Location2p11.1-q11.2
SummaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MRPL19

Proteins

39S ribosomal protein L19, mitochondrial
Refseq ID:NP_055578
Protein GI:94557305
UniProt ID:P49406
mRNA ID:NM_014763
Length:292
RefSeq Status:
MAACIAAGHWAAMGLGRSFQAARTLLPPPASIACRVHAGPVRQQSTGPSEPGAFQPPPKPVIVDKHRPVEPERRFLSPEFIPRRGRTDPLKFQIERKDML
ERRKVLHIPEFYVGSILRVTTADPYASGKISQFLGICIQRSGRGLGATFILRNVIEGQGVEICFELYNPRVQEIQVVKLEKRLDDSLLYLRDALPEYSTF
DVNMKPVVQEPNQKVPVNELKVKMKPKPWSKRWERPNFNIKGIRFDLCLTEQQMKEAQKWNQPWLEFDMMREYDTSKIEAAIWKEIEASKRS
 
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