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MGP Database

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MGP004426

Ontology/Pathway Information

Entrez Gene ID	10998
Gene Name	solute carrier family 27 (fatty acid transporter), member 5
Gene Symbol	SLC27A5
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009925	IEA:Ensembl	C	basal plasma membrane
GO:0005783	IDA:UniProtKB	C	endoplasmic reticulum
GO:0005789	TAS:Reactome	C	endoplasmic reticulum membrane
GO:0030176	IDA:UniProtKB	C	integral component of endoplasmic reticulum membrane
GO:0043234	IEA:Ensembl	C	protein complex
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0047747	IEA:UniProtKB-EC	F	cholate-CoA ligase activity
GO:0015245	IEA:Ensembl	F	fatty acid transporter activity
GO:0031957	IDA:UniProtKB	F	very long-chain fatty acid-CoA ligase activity
GO:0015721	TAS:Reactome	P	bile acid and bile salt transport
GO:0006699	IDA:UniProtKB	P	bile acid biosynthetic process
GO:0008206	TAS:Reactome	P	bile acid metabolic process
GO:0046951	IEA:Ensembl	P	ketone body biosynthetic process
GO:0015911	IEA:Ensembl	P	plasma membrane long-chain fatty acid transport
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006642	IEA:Ensembl	P	triglyceride mobilization
GO:0000038	IDA:UniProtKB	P	very long-chain fatty acid metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_11040	Bile acid and bile salt metabolism
REACT_111217	Metabolism
REACT_22258	Metabolism of lipids and lipoproteins
REACT_11042	Recycling of bile acids and salts
REACT_11054	Synthesis of bile acids and bile salts
REACT_11053	Synthesis of bile acids and bile salts via 24-hydroxycholesterol
REACT_11041	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol

SMP Pathway Links

SMP ID	Description
SMP00720	27-Hydroxylase Deficiency
SMP00035	Bile Acid Biosynthesis
SMP00315	Cerebrotendinous Xanthomatosis (CTX)
SMP00314	Congenital Bile Acid Synthesis Defect Type II
SMP00318	Congenital Bile Acid Synthesis Defect Type III
SMP00317	Familial Hypercholanemia (FHCA)
SMP00316	Zellweger Syndrome